biostudies-literatureUnknown74(2)Malhotra C<h4>Background</h4>Dementia-the seventh leading cause of death globally-is most prevalent in Asia, home to over half of those affected. Yet, palliative approaches to dementia, endorsed by the World Health Organization (WHO) Global Action Plan on the Public Health Response to Dementia, and focused on improving quality of life through a holistic and person-centered approach, are largely absent in the region.<h4>Methods</h4>We reviewed the available literature related to end-of-life experiences with advanced dementia from countries in the WHO South-east Asian and Western Pacific regions. We used the Consolidated Framework for Implementation Research to synthesize barriers and facilitators to implementing a palliative approach to dementia and propose a research agenda.<h4>Results</h4>Broad barJournal of the American Geriatrics Society522-531https://www.ebi.ac.uk/biostudies/studies/S-EPMC12911550biostudies-literatureThe End of Life With Dementia in Asian Countries: Barriers, Facilitators and a Research Agenda for Advancing a Palliative Approach.PMC12911550Ramakrishnan CAndres EBMalhotra CfalseThe End of Life With Dementia in Asian Countries: Barriers, Facilitators and a Research Agenda for Advancing a Palliative Approach.<h4>Background</h4>Dementia-the seventh leading cause of death globally-is most prevalent in Asia, home to over half of those affected. Yet, palliative approaches to dementia, endorsed by the World Health Organization (WHO) Global Action Plan on the Public Health Response to Dementia, and focused on improving quality of life through a holistic and person-centered approach, are largely absent in the region.<h4>Methods</h4>We reviewed the available literature related to end-of-life experiences with advanced dementia from countries in the WHO South-east Asian and Western Pacific regions. We used the Consolidated Framework for Implementation Research to synthesize barriers and facilitators to implementing a palliative approach to dementia and propose a research agenda.<h4>Results</h4>Broad bar2026-01-01T00:00:00Z2026 Feb2026-07-16T03:16:25.704Z2026-07-09T10:31:01.038ZS-EPMC129115504153118810.1111/jgs.70283