{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Marin-Carvajal S"],"funding":["Departamento Administrativo de Ciencia, Tecnología e Innovación"],"pagination":["e0342479"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12912593"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["21(2)"],"pubmed_abstract":["The Aspergillus genus comprises fungi that are widely distributed in nature. Several Aspergillus sections are important for recycling organic matter; while the Fumigati section is classically associated with compost, the Terrei section also plays a relevant role in this process. Aspergillus hortae is a species from this section that has been isolated from clinical samples, but its role as a pathogenic agent is unclear. In this study, we analysed three clinical isolates of A. hortae from Colombia, initially misidentified as A. terreus. Morphological characterization at 26 °C and 37 °C confirmed its thermotolerant nature. Whole-genome sequencing enabled accurate species identification and revealed phylogenetic divergence from the reference genome. Antifungal susceptibility testing (EUCAST br"],"journal":["PloS one"],"pubmed_title":["Whole-genome sequencing, phenotypic characterization, and antifungal susceptibility profiles of three Aspergillus hortae clinical isolates from Colombia."],"pmcid":["PMC12912593"],"funding_grant_id":["221384467683"],"pubmed_authors":["Marin-Carvajal S","Rua-Giraldo A","McEwen JG","Zuleta MC","Torres S","Quiceno Torres M","Lopez AM","Gomez OM","Hernandez O","Borges CL","Garcia AM"],"additional_accession":[]},"is_claimable":false,"name":"Whole-genome sequencing, phenotypic characterization, and antifungal susceptibility profiles of three Aspergillus hortae clinical isolates from Colombia.","description":"The Aspergillus genus comprises fungi that are widely distributed in nature. Several Aspergillus sections are important for recycling organic matter; while the Fumigati section is classically associated with compost, the Terrei section also plays a relevant role in this process. Aspergillus hortae is a species from this section that has been isolated from clinical samples, but its role as a pathogenic agent is unclear. In this study, we analysed three clinical isolates of A. hortae from Colombia, initially misidentified as A. terreus. Morphological characterization at 26 °C and 37 °C confirmed its thermotolerant nature. Whole-genome sequencing enabled accurate species identification and revealed phylogenetic divergence from the reference genome. Antifungal susceptibility testing (EUCAST br","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026","modification":"2026-07-16T05:14:16.566Z","creation":"2026-07-09T10:38:10.462Z"},"accession":"S-EPMC12912593","cross_references":{"pubmed":["41701753"],"doi":["10.1371/journal.pone.0342479"]}}