{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Gao M"],"funding":["NIGMS NIH HHS"],"pagination":["7931-44"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC1291280"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["187(23)"],"pubmed_abstract":["Quorum sensing (QS) in Sinorhizobium meliloti, the N-fixing bacterial symbiont of Medicago host plants, involves at least half a dozen different N-acyl homoserine lactone (AHL) signals and perhaps an equal number of AHL receptors. The accumulation of 55 proteins was found to be dependent on SinI, the AHL synthase, and/or on ExpR, one of the AHL receptors. Gas chromatography-mass spectrometry and electrospray ionization tandem mass spectrometry identified 3-oxo-C(14)-homoserine lactone (3-oxo-C(14)-HSL), C(16)-HSL, 3-oxo-C(16)-HSL, C(16:1)-HSL, and 3-oxo-C(16:1)-HSL as the sinI-dependent AHL QS signals accumulated by the 8530 expR(+) strain under the conditions used for proteome analysis. The 8530 expR(+) strain secretes additional, unidentified QS-active compounds. Addition of 200 nM C(14)"],"journal":["Journal of bacteriology"],"pubmed_title":["sinI- and expR-dependent quorum sensing in Sinorhizobium meliloti."],"pmcid":["PMC1291280"],"funding_grant_id":["R01 GM042893"],"pubmed_authors":["Robinson JB","Gao M","Eberhard A","Gronquist MR","Chen H","Rolfe BG","Bauer WD"],"additional_accession":[]},"is_claimable":false,"name":"sinI- and expR-dependent quorum sensing in Sinorhizobium meliloti.","description":"Quorum sensing (QS) in Sinorhizobium meliloti, the N-fixing bacterial symbiont of Medicago host plants, involves at least half a dozen different N-acyl homoserine lactone (AHL) signals and perhaps an equal number of AHL receptors. The accumulation of 55 proteins was found to be dependent on SinI, the AHL synthase, and/or on ExpR, one of the AHL receptors. Gas chromatography-mass spectrometry and electrospray ionization tandem mass spectrometry identified 3-oxo-C(14)-homoserine lactone (3-oxo-C(14)-HSL), C(16)-HSL, 3-oxo-C(16)-HSL, C(16:1)-HSL, and 3-oxo-C(16:1)-HSL as the sinI-dependent AHL QS signals accumulated by the 8530 expR(+) strain under the conditions used for proteome analysis. The 8530 expR(+) strain secretes additional, unidentified QS-active compounds. Addition of 200 nM C(14)","dates":{"release":"2005-01-01T00:00:00Z","publication":"2005 Dec","modification":"2025-04-04T09:51:38.596Z","creation":"2025-02-19T04:02:07.515Z"},"accession":"S-EPMC1291280","cross_references":{"pubmed":["16291666"],"doi":["10.1128/jb.187.23.7931-7944.2005","10.1128/JB.187.23.7931-7944.2005"]}}