{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Lian Q"],"funding":["Shenzhen Medical Research Fund"],"pagination":["146"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12914919"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["26(1)"],"pubmed_abstract":["<h4>Background</h4>The \"male-female health-survival paradox\" describes women's longer lifespan despite a greater burden of non-fatal chronic conditions-a phenomenon rarely examined in surgical settings. This study investigated whether this paradox exists in a national cohort of frail patients undergoing hip replacement and explored its underlying mechanisms. We hypothesized that in this cohort: (1) female patients would be less healthy, presenting with a higher prevalence of frailty, older age, and a higher Charlson Comorbidity Index (CCI); and (2) frail men would experience higher in-hospital mortality.<h4>Methods</h4>A retrospective cohort study was conducted using the US National Inpatient Sample (2005-2014) A frailty-defining diagnosis cluster was employed to identify frail individuals"],"journal":["BMC surgery"],"pubmed_title":["The \"male-female health-survival paradox\" in frail patients undergoing hip replacement."],"pmcid":["PMC12914919"],"funding_grant_id":["A2402016","C2501025"],"pubmed_authors":["Li G","Du D","Lian Y","Wang J","Lian Q","Yu Y"],"additional_accession":[]},"is_claimable":false,"name":"The \"male-female health-survival paradox\" in frail patients undergoing hip replacement.","description":"<h4>Background</h4>The \"male-female health-survival paradox\" describes women's longer lifespan despite a greater burden of non-fatal chronic conditions-a phenomenon rarely examined in surgical settings. This study investigated whether this paradox exists in a national cohort of frail patients undergoing hip replacement and explored its underlying mechanisms. We hypothesized that in this cohort: (1) female patients would be less healthy, presenting with a higher prevalence of frailty, older age, and a higher Charlson Comorbidity Index (CCI); and (2) frail men would experience higher in-hospital mortality.<h4>Methods</h4>A retrospective cohort study was conducted using the US National Inpatient Sample (2005-2014) A frailty-defining diagnosis cluster was employed to identify frail individuals","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Jan","modification":"2026-07-16T06:33:41.005Z","creation":"2026-07-09T10:39:14.877Z"},"accession":"S-EPMC12914919","cross_references":{"pubmed":["41580723"],"doi":["10.1186/s12893-026-03532-9"]}}