{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Desai G"],"funding":["National Institute of Environmental Health Sciences","U.S. Department of Agriculture","New Jersey Health Foundation","NIEHS NIH HHS","Royal Society–Wellcome Sir Henry Dale Fellowship","Royal Society-Wellcome Sir Henry Dale Fellowship","Bleu Garde, LLC","UKRI Future Leaders Fellowship"],"pagination":["e0233525"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12915340"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["92(2)"],"pubmed_abstract":["The COVID-19 outbreak brought to the fore the importance of airborne transmission in spreading human infectious diseases and highlighted the need for sustainable mitigation strategies. Triethylene glycol (TEG) has been documented as having microbicidal capabilities and has been proposed as one such mitigation strategy. Aerosolized TEG exhibits antimicrobial activity against airborne microorganisms. Grignard Pure Technology was developed to safely aerosolize TEG for decontamination of enclosed spaces. Here, we show that this TEG formulation effectively inactivates airborne microorganisms, resulting in 2 to 4.5 net log reduction in concentration of viable bacteria, viruses, and mycobacteria within 30-60 min at TEG concentration (aerosol + vapor) of ~0.7 mg/m<sup>3</sup>, which is well within"],"journal":["Applied and environmental microbiology"],"pubmed_title":["Inactivation of airborne pathogen surrogates by triethylene glycol."],"pmcid":["PMC12915340"],"funding_grant_id":["208790/Z/17/Z","MR/Y017552/1","PC104-25","P30 ES05022","1025241"],"pubmed_authors":["Edgar R","Ramachandran G","Desai G","Caravanos J","Grignard E","Jordan W","Balarashti J","Mainelis G","Goldman E"],"additional_accession":[]},"is_claimable":false,"name":"Inactivation of airborne pathogen surrogates by triethylene glycol.","description":"The COVID-19 outbreak brought to the fore the importance of airborne transmission in spreading human infectious diseases and highlighted the need for sustainable mitigation strategies. Triethylene glycol (TEG) has been documented as having microbicidal capabilities and has been proposed as one such mitigation strategy. Aerosolized TEG exhibits antimicrobial activity against airborne microorganisms. Grignard Pure Technology was developed to safely aerosolize TEG for decontamination of enclosed spaces. Here, we show that this TEG formulation effectively inactivates airborne microorganisms, resulting in 2 to 4.5 net log reduction in concentration of viable bacteria, viruses, and mycobacteria within 30-60 min at TEG concentration (aerosol + vapor) of ~0.7 mg/m<sup>3</sup>, which is well within","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Feb","modification":"2026-07-16T06:34:37.918Z","creation":"2026-07-09T10:39:19.231Z"},"accession":"S-EPMC12915340","cross_references":{"pubmed":["41575207"],"doi":["10.1128/aem.02335-25"]}}