biostudies-literatureUnknown9Siegel ZM<h4>Background</h4>Digital health tools are increasingly vital in rural health care due to widespread hospital closures and the rapid adoption of telehealth during the COVID-19 pandemic. Rural older adults, a uniquely vulnerable population, face barriers to accessing these tools due to rurality and usability challenges. Although a growing body of literature examines the acceptability and usability of digital tools among rural older adults, no study has synthesized this research to establish best practices.<h4>Objective</h4>This study aims to review existing literature on digital health tools for rural older adults, highlighting key lessons learned about their acceptability and identifying strategies to improve usability for this population.<h4>Methods</h4>Following the PRISMA (Preferred ReJMIR aginge70012https://www.ebi.ac.uk/biostudies/studies/S-EPMC12917484biostudies-literatureLessons Learned About Digital Health Tool Acceptability Among Rural Older Adults: Systematic Review Guided by the Technology Acceptance Model.PMC12917484Siegel ZMPai JLewis MWMiller CHQuinkert EfalseLessons Learned About Digital Health Tool Acceptability Among Rural Older Adults: Systematic Review Guided by the Technology Acceptance Model.<h4>Background</h4>Digital health tools are increasingly vital in rural health care due to widespread hospital closures and the rapid adoption of telehealth during the COVID-19 pandemic. Rural older adults, a uniquely vulnerable population, face barriers to accessing these tools due to rurality and usability challenges. Although a growing body of literature examines the acceptability and usability of digital tools among rural older adults, no study has synthesized this research to establish best practices.<h4>Objective</h4>This study aims to review existing literature on digital health tools for rural older adults, highlighting key lessons learned about their acceptability and identifying strategies to improve usability for this population.<h4>Methods</h4>Following the PRISMA (Preferred Re2026-01-01T00:00:00Z2026 Feb2026-07-16T10:05:05.76Z2026-07-09T10:48:40.134ZS-EPMC129174844163773710.2196/70012