{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["11(6)"],"submitter":["Akgun CE"],"pubmed_abstract":["This study focuses on the synthesis of OA@ZnFe<sub>2</sub>O<sub>4</sub> NPs and the investigation of their structural, magnetic, and biological characteristics as well as their pH-responsive drug release behavior for potential biomedical use. The particles with an average particle size of ∼23 nm exhibited a single-phase spinel structure and superparamagnetic behavior. DOX was successfully loaded onto the NPs with a remarkably high efficiency (∼99%). In vitro release studies demonstrated that the OA@ZnFe<sub>2</sub>O<sub>4</sub> NPs exhibited a pH-dependent release behavior in phosphate-buffered saline and citrate buffers. The release rate was highest at pH 4.5, followed by pH 6.5 and then pH 7.4 in both buffer media. The OA@ZnFe<sub>2</sub>O<sub>4</sub> NPs (0.5 mg/mL) in citrate buffer at"],"journal":["ACS omega"],"pagination":["9160-9175"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12917698"],"repository":["biostudies-literature"],"pubmed_title":["Oleic Acid-Coated Zinc Ferrite Nanocubes: A Promising Nanocarrier for Neuroblastoma Therapy."],"pmcid":["PMC12917698"],"pubmed_authors":["Ozdemir FM","Akgun CE","Demircan T","Abaka I","Gulsu A"],"additional_accession":[]},"is_claimable":false,"name":"Oleic Acid-Coated Zinc Ferrite Nanocubes: A Promising Nanocarrier for Neuroblastoma Therapy.","description":"This study focuses on the synthesis of OA@ZnFe<sub>2</sub>O<sub>4</sub> NPs and the investigation of their structural, magnetic, and biological characteristics as well as their pH-responsive drug release behavior for potential biomedical use. The particles with an average particle size of ∼23 nm exhibited a single-phase spinel structure and superparamagnetic behavior. DOX was successfully loaded onto the NPs with a remarkably high efficiency (∼99%). In vitro release studies demonstrated that the OA@ZnFe<sub>2</sub>O<sub>4</sub> NPs exhibited a pH-dependent release behavior in phosphate-buffered saline and citrate buffers. The release rate was highest at pH 4.5, followed by pH 6.5 and then pH 7.4 in both buffer media. The OA@ZnFe<sub>2</sub>O<sub>4</sub> NPs (0.5 mg/mL) in citrate buffer at","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Feb","modification":"2026-07-16T18:01:20.827Z","creation":"2026-07-09T11:10:44.013Z"},"accession":"S-EPMC12917698","cross_references":{"pubmed":["41726676"],"doi":["10.1021/acsomega.5c08155"]}}