{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["26(1)"],"submitter":["Yamakawa Y"],"pubmed_abstract":["<h4>Background</h4>Incisional hernia is the most common long-term complication after abdominal surgery, including minimally invasive colorectal procedures. In Japan, fascial closure of small midline incisions is generally performed using interrupted suturing, but high-quality evidence comparing continuous barbed suturing with interrupted suturing is limited. Continuous closure may reduce the risk of incisional hernia; however, robust randomized data in laparoscopic and robot-assisted colorectal surgery are lacking. This study aims to determine whether continuous barbed suturing is superior to conventional interrupted suturing in preventing incisional hernia after minimally invasive colorectal cancer surgery.<h4>Methods</h4>The HIBISCUS trial is a multicenter, prospective, open-label, rando"],"journal":["BMC surgery"],"pagination":["151"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12918296"],"repository":["biostudies-literature"],"pubmed_title":["HIBISCUS trial (hernia incidence with continuous barbed vs interrupted suturing in colorectal surgery with small incisions): a contemporary study protocol for a multicenter randomized controlled trial."],"pmcid":["PMC12918296"],"pubmed_authors":["Yamakawa Y","Suzuki T","Otani T","Hirokawa T","Harata K","Yamamoto T","Shiga K","Asai H","Nakai N","Kato J","Uehara S","Kato A","Sawai M","Ushigome H","Takahashi H","Takiguchi S"],"additional_accession":[]},"is_claimable":false,"name":"HIBISCUS trial (hernia incidence with continuous barbed vs interrupted suturing in colorectal surgery with small incisions): a contemporary study protocol for a multicenter randomized controlled trial.","description":"<h4>Background</h4>Incisional hernia is the most common long-term complication after abdominal surgery, including minimally invasive colorectal procedures. In Japan, fascial closure of small midline incisions is generally performed using interrupted suturing, but high-quality evidence comparing continuous barbed suturing with interrupted suturing is limited. Continuous closure may reduce the risk of incisional hernia; however, robust randomized data in laparoscopic and robot-assisted colorectal surgery are lacking. This study aims to determine whether continuous barbed suturing is superior to conventional interrupted suturing in preventing incisional hernia after minimally invasive colorectal cancer surgery.<h4>Methods</h4>The HIBISCUS trial is a multicenter, prospective, open-label, rando","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Jan","modification":"2026-07-16T09:17:43.896Z","creation":"2026-07-09T10:46:57.213Z"},"accession":"S-EPMC12918296","cross_references":{"pubmed":["41588403"],"doi":["10.1186/s12893-026-03528-5"]}}