biostudies-literatureUnknown26(1)Yamakawa Y<h4>Background</h4>Incisional hernia is the most common long-term complication after abdominal surgery, including minimally invasive colorectal procedures. In Japan, fascial closure of small midline incisions is generally performed using interrupted suturing, but high-quality evidence comparing continuous barbed suturing with interrupted suturing is limited. Continuous closure may reduce the risk of incisional hernia; however, robust randomized data in laparoscopic and robot-assisted colorectal surgery are lacking. This study aims to determine whether continuous barbed suturing is superior to conventional interrupted suturing in preventing incisional hernia after minimally invasive colorectal cancer surgery.<h4>Methods</h4>The HIBISCUS trial is a multicenter, prospective, open-label, randoBMC surgery151https://www.ebi.ac.uk/biostudies/studies/S-EPMC12918296biostudies-literatureHIBISCUS trial (hernia incidence with continuous barbed vs interrupted suturing in colorectal surgery with small incisions): a contemporary study protocol for a multicenter randomized controlled trial.PMC12918296Yamakawa YSuzuki TOtani THirokawa THarata KYamamoto TShiga KAsai HNakai NKato JUehara SKato ASawai MUshigome HTakahashi HTakiguchi SfalseHIBISCUS trial (hernia incidence with continuous barbed vs interrupted suturing in colorectal surgery with small incisions): a contemporary study protocol for a multicenter randomized controlled trial.<h4>Background</h4>Incisional hernia is the most common long-term complication after abdominal surgery, including minimally invasive colorectal procedures. In Japan, fascial closure of small midline incisions is generally performed using interrupted suturing, but high-quality evidence comparing continuous barbed suturing with interrupted suturing is limited. Continuous closure may reduce the risk of incisional hernia; however, robust randomized data in laparoscopic and robot-assisted colorectal surgery are lacking. This study aims to determine whether continuous barbed suturing is superior to conventional interrupted suturing in preventing incisional hernia after minimally invasive colorectal cancer surgery.<h4>Methods</h4>The HIBISCUS trial is a multicenter, prospective, open-label, rando2026-01-01T00:00:00Z2026 Jan2026-07-16T09:17:43.896Z2026-07-09T10:46:57.213ZS-EPMC129182964158840310.1186/s12893-026-03528-5