{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["16(2)"],"submitter":["Catherine Chan KL"],"pubmed_abstract":["<h4>Introduction</h4>Soft robotic gloves (SRGs) integrated with brain-computer interfaces (BCIs) have demonstrated potential in facilitating motor recovery after stroke by enabling active, intention-driven rehabilitation. Emerging evidence suggests that incorporating vibrotactile stimulation (VTS) into SRG-BCI systems may further enhance sensorimotor feedback. The objective of this study is to evaluate the therapeutic efficacy and underlying neural mechanisms of BCI-driven, intention-based glove activation compared with automated glove-assisted training, with VTS applied identically in both groups.<h4>Methods and analysis</h4>This multicentre, single-blind, randomised controlled trial will involve 48 post-stroke patients within 1 week to 3 months after stroke onset, with stratification by "],"journal":["BMJ open"],"pagination":["e110321"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12918676"],"repository":["biostudies-literature"],"pubmed_title":["Efficacy and neural mechanisms of a vibrotactile-enhanced, brain-controlled soft robotic glove for upper limb rehabilitation after stroke: a multicentre randomised controlled trial protocol."],"pmcid":["PMC12918676"],"pubmed_authors":["Zhang W","Catherine Chan KL","Huang S","Xu B","Dai W","Yan C","Luo Y","Wang X","Shen Y","Cheng Y"],"additional_accession":[]},"is_claimable":false,"name":"Efficacy and neural mechanisms of a vibrotactile-enhanced, brain-controlled soft robotic glove for upper limb rehabilitation after stroke: a multicentre randomised controlled trial protocol.","description":"<h4>Introduction</h4>Soft robotic gloves (SRGs) integrated with brain-computer interfaces (BCIs) have demonstrated potential in facilitating motor recovery after stroke by enabling active, intention-driven rehabilitation. Emerging evidence suggests that incorporating vibrotactile stimulation (VTS) into SRG-BCI systems may further enhance sensorimotor feedback. The objective of this study is to evaluate the therapeutic efficacy and underlying neural mechanisms of BCI-driven, intention-based glove activation compared with automated glove-assisted training, with VTS applied identically in both groups.<h4>Methods and analysis</h4>This multicentre, single-blind, randomised controlled trial will involve 48 post-stroke patients within 1 week to 3 months after stroke onset, with stratification by ","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Feb","modification":"2026-07-16T10:05:25.58Z","creation":"2026-07-09T10:48:44.2Z"},"accession":"S-EPMC12918676","cross_references":{"pubmed":["41708167"],"doi":["10.1136/bmjopen-2025-110321"]}}