biostudies-literatureUnknown13Wei R<h4>Objective</h4>To describe the prenatal ultrasound characteristics of persistent left superior vena cava (PLSVC) in fetuses and its correlation with related malformations, chromosomal abnormalities, and clinical outcomes.<h4>Methods</h4>A 10-year retrospective analysis of the clinical and ultrasound data of 898 fetuses diagnosed with PLSVC at our center was conducted. Ultrasound characteristics of PLSVC type were summarised systematically, and incidence rates of abnormalities and pregnancy outcomes of PLSVC types were determined.<h4>Results</h4>Diagnosing PLSVC requires the 4CV, 3VV and 3VT views, while auxiliary classification requires parasagittal and innominate vein views. PLSVC ultrasound features include coronary sinus dilation and an additional vascular cross-section on the left sFrontiers in medicine1743489https://www.ebi.ac.uk/biostudies/studies/S-EPMC12920434biostudies-literaturePrenatal ultrasound diagnosis and prognosis of persistent left superior vena cava: a 10-year retrospective cohort study at a single center in China.PMC12920434Wei RLing WWu QLyu GWeng ZGong JWang YfalsePrenatal ultrasound diagnosis and prognosis of persistent left superior vena cava: a 10-year retrospective cohort study at a single center in China.<h4>Objective</h4>To describe the prenatal ultrasound characteristics of persistent left superior vena cava (PLSVC) in fetuses and its correlation with related malformations, chromosomal abnormalities, and clinical outcomes.<h4>Methods</h4>A 10-year retrospective analysis of the clinical and ultrasound data of 898 fetuses diagnosed with PLSVC at our center was conducted. Ultrasound characteristics of PLSVC type were summarised systematically, and incidence rates of abnormalities and pregnancy outcomes of PLSVC types were determined.<h4>Results</h4>Diagnosing PLSVC requires the 4CV, 3VV and 3VT views, while auxiliary classification requires parasagittal and innominate vein views. PLSVC ultrasound features include coronary sinus dilation and an additional vascular cross-section on the left s2026-01-01T00:00:00Z20262026-07-09T12:13:30.289Z2026-07-09T11:15:12.35ZS-EPMC129204344172860410.3389/fmed.2026.1743489