{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Castells A"],"funding":["Instituto de Salud Carlos III","Fundación Científica Asociación Española Contra el Cáncer"],"pagination":["e70169"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12920682"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["14(2)"],"pubmed_abstract":["<h4>Background</h4>Colorectal cancer (CRC) screening is effective and cost-effective in average-risk individuals. The COLONPREV study recently showed that individuals invited to a faecal immunochemical test (FIT) were more likely to participate in screening than those invited to colonoscopy, and that FIT-based screening was non-inferior to colonoscopy with respect to CRC-related mortality and CRC incidence.<h4>Objective</h4>To assess whether the outcomes of colonoscopy- and FIT-based screening differ according to sex and age in the invited population.<h4>Methods</h4>Presumptively healthy men and women aged 50-69 years were randomised to either a one-time screening colonoscopy or biennial FIT. In this analysis, we report participation and crossover rates, CRC-related mortality, CRC incidenc"],"journal":["United European gastroenterology journal"],"pubmed_title":["Sex- and Age-Stratified Outcomes of Colonoscopy Versus Faecal Immunochemical Testing: Post-Analysis of the COLONPREV Study."],"pmcid":["PMC12920682"],"funding_grant_id":["GCB13131592CAST","PI08/90717","AECC07185"],"pubmed_authors":["Cubiella J","Morillas JD","Bujanda L","Coll-Vinent B","Castan-Cameo S","Andreu M","Diaz-Tasende J","Castells A","Serra-Burriel M","COLONPREV study investigators","Jover R","Lanas A","Carballo F","Frias-Arrocha E","Ono A","Quintero E","Hernandez C","Salas D"],"additional_accession":[]},"is_claimable":false,"name":"Sex- and Age-Stratified Outcomes of Colonoscopy Versus Faecal Immunochemical Testing: Post-Analysis of the COLONPREV Study.","description":"<h4>Background</h4>Colorectal cancer (CRC) screening is effective and cost-effective in average-risk individuals. The COLONPREV study recently showed that individuals invited to a faecal immunochemical test (FIT) were more likely to participate in screening than those invited to colonoscopy, and that FIT-based screening was non-inferior to colonoscopy with respect to CRC-related mortality and CRC incidence.<h4>Objective</h4>To assess whether the outcomes of colonoscopy- and FIT-based screening differ according to sex and age in the invited population.<h4>Methods</h4>Presumptively healthy men and women aged 50-69 years were randomised to either a one-time screening colonoscopy or biennial FIT. In this analysis, we report participation and crossover rates, CRC-related mortality, CRC incidenc","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Mar","modification":"2026-07-16T15:09:50.541Z","creation":"2026-07-09T11:03:31.557Z"},"accession":"S-EPMC12920682","cross_references":{"pubmed":["41715250"],"doi":["10.1002/ueg2.70169"]}}