{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Zhao P"],"funding":["Hong Kong Polytechnic University","Government of the Hong Kong Special Administrative Region"],"pagination":["2249-2255"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12922175"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["26(6)"],"pubmed_abstract":["Optical nanofibers (ONF) have emerged as versatile platforms for studying light-gas interactions at the micro/nanoscale, yet existing ONF gas sensors remain limited in detection sensitivity. Here, we report a polarization-mode photothermal interferometry technique that precisely measures the gas absorption-induced phase difference between two polarization states of the symmetric supermode of a single-mode ONF coupler. The high power density and large evanescent field associated with the ONF coupler enhance the efficiency of photothermal phase modulation, while the strong waveguide birefringence and noise-immune differential phase detection confer environmental immunity, jointly yielding an order-of-magnitude enhancement in the signal-to-noise ratio. With a 2 cm-long overcoupled ONF coupler"],"journal":["Nano letters"],"pubmed_title":["Ultrasensitive Gas Detection via Polarization-Mode Photothermal Interferometry in a Single-Mode Nanofiber Coupler."],"pmcid":["PMC12922175"],"funding_grant_id":["1-ZVY4","1-W23D","15223421","1-CDJ6"],"pubmed_authors":["Jin W","Ho HL","Zhao S","Zhao P","Bao H"],"additional_accession":[]},"is_claimable":false,"name":"Ultrasensitive Gas Detection via Polarization-Mode Photothermal Interferometry in a Single-Mode Nanofiber Coupler.","description":"Optical nanofibers (ONF) have emerged as versatile platforms for studying light-gas interactions at the micro/nanoscale, yet existing ONF gas sensors remain limited in detection sensitivity. Here, we report a polarization-mode photothermal interferometry technique that precisely measures the gas absorption-induced phase difference between two polarization states of the symmetric supermode of a single-mode ONF coupler. The high power density and large evanescent field associated with the ONF coupler enhance the efficiency of photothermal phase modulation, while the strong waveguide birefringence and noise-immune differential phase detection confer environmental immunity, jointly yielding an order-of-magnitude enhancement in the signal-to-noise ratio. With a 2 cm-long overcoupled ONF coupler","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Feb","modification":"2026-07-16T12:33:08.519Z","creation":"2026-07-09T10:55:03.754Z"},"accession":"S-EPMC12922175","cross_references":{"pubmed":["41629067"],"doi":["10.1021/acs.nanolett.5c06094"]}}