{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Zhao M"],"funding":["Natural Science Foundation of Shaanxi Province","National Key Research and Development Programme of China","Humanities and Social Science Fund of Ministry of Education of China"],"pagination":["749-767"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12924801"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["15(3)"],"pubmed_abstract":["<h4>Introduction</h4>Implementing pre-exposure prophylaxis (PrEP) is hindered by a significant \"PrEP Cliff\", a sharp decline from willingness to uptake and adherence. This study aimed to integrate status quo bias theory with a dual-process model, seeking to understand how this bias influences the PrEP cascade among men who have sex with men (MSM) in China.<h4>Methods</h4>A cross-sectional survey was conducted among 1022 MSM across six provinces in China from November 2024 to February 2025. Through regression models, we tested a moderated mediation framework to examine how status quo bias influenced PrEP willingness, uptake, and adherence, focusing on the mediating role of PrEP resistance intention and the moderating role of condom-use inertia.<h4>Results</h4>Participants were generally you"],"journal":["Infectious diseases and therapy"],"pubmed_title":["How Status Quo Bias Shapes Willingness, Uptake, and Adherence to PrEP Among Chinese MSM: A Behavioral Economics Perspective."],"pmcid":["PMC12924801"],"funding_grant_id":["2022YFC2505100","24YJC840051","2022YFC2304900","2025JC-YBQN-1106"],"pubmed_authors":["Zhao M","Ong JJ","Zhang Y","Ji F","Zhang L","Tang W","Zhao X","Yin Z"],"additional_accession":[]},"is_claimable":false,"name":"How Status Quo Bias Shapes Willingness, Uptake, and Adherence to PrEP Among Chinese MSM: A Behavioral Economics Perspective.","description":"<h4>Introduction</h4>Implementing pre-exposure prophylaxis (PrEP) is hindered by a significant \"PrEP Cliff\", a sharp decline from willingness to uptake and adherence. This study aimed to integrate status quo bias theory with a dual-process model, seeking to understand how this bias influences the PrEP cascade among men who have sex with men (MSM) in China.<h4>Methods</h4>A cross-sectional survey was conducted among 1022 MSM across six provinces in China from November 2024 to February 2025. Through regression models, we tested a moderated mediation framework to examine how status quo bias influenced PrEP willingness, uptake, and adherence, focusing on the mediating role of PrEP resistance intention and the moderating role of condom-use inertia.<h4>Results</h4>Participants were generally you","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Mar","modification":"2026-07-16T15:18:09.738Z","creation":"2026-07-11T03:07:27.721Z"},"accession":"S-EPMC12924801","cross_references":{"pubmed":["41575704"],"doi":["10.1007/s40121-025-01296-y"]}}