{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Renzer G"],"funding":["U.S. Department of Defense","Max-Planck-Gesellschaft","National Science Foundation"],"pagination":["2068-2076"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12926935"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["130(7)"],"pubmed_abstract":["Perfluorinated acids such as perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS) constitute major environmental pollutants with largely unknown effects on biological ice nucleators (INs), which are crucial for freezing-associated processes in nature. One of the most efficient and abundant INs are bacterial ice-nucleating proteins (INpros). Their record-breaking freezing efficiency relies on assembling large functional aggregates, which, while highly active, show high sensitivity to environmental conditions. This study demonstrates that PFOS and PFOA destroy INpro aggregates, significantly reducing the bacterial ice nucleation efficiency near 0 °C. Exposure to perfluorinated compounds at concentrations of 10 mg/L is sufficient to alter the bacterial IN activity and make th"],"journal":["The journal of physical chemistry. B"],"pubmed_title":["Impact of Perfluorinated Organic Acids on Bacterial Ice Nucleators."],"pmcid":["PMC12926935"],"funding_grant_id":["2336558","FA9550-24-1-0197"],"pubmed_authors":["Renzer G","Meister K","Bonn M","Eufemio RJ"],"additional_accession":[]},"is_claimable":false,"name":"Impact of Perfluorinated Organic Acids on Bacterial Ice Nucleators.","description":"Perfluorinated acids such as perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS) constitute major environmental pollutants with largely unknown effects on biological ice nucleators (INs), which are crucial for freezing-associated processes in nature. One of the most efficient and abundant INs are bacterial ice-nucleating proteins (INpros). Their record-breaking freezing efficiency relies on assembling large functional aggregates, which, while highly active, show high sensitivity to environmental conditions. This study demonstrates that PFOS and PFOA destroy INpro aggregates, significantly reducing the bacterial ice nucleation efficiency near 0 °C. Exposure to perfluorinated compounds at concentrations of 10 mg/L is sufficient to alter the bacterial IN activity and make th","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Feb","modification":"2026-07-16T18:24:44.504Z","creation":"2026-07-09T11:15:06.815Z"},"accession":"S-EPMC12926935","cross_references":{"pubmed":["41666376"],"doi":["10.1021/acs.jpcb.5c07036"]}}