biostudies-literatureLiu XEunice Kennedy Shriver National Institute of Child Health and Human DevelopmentNCATS NIH HHSNCI NIH HHSNLM NIH HHSNIGMS NIH HHSe70096https://www.ebi.ac.uk/biostudies/studies/S-EPMC12929201biostudies-literatureUnknown46(3)Pregnant women and children have been underrepresented in clinical studies due to ethical concerns and perceived vulnerabilities. This resulted in a significant gap in knowledge regarding the safety and efficacy of medications for these populations. Maternal and Pediatric PRecision In Therapeutics Knowledge Portal (MPRINT-KP) is designed to provide a comprehensive view of pharmacokinetic, pharmaco-epidemiology, and clinical trial research evidence in maternal and pediatric patient populations. MPRINT-KP Silver was generated upon BioBERT models, due to their supreme performance in classifying pharmacokinetic, pharmaco-epidemiology, and clinical trial papers from PubMed, with an F1-score > 0.91. As of April 1, 2025, MPRINT-KP Silver contains 758,560 clinical pharmacology research papers in mPharmacotherapyMaternal and Pediatric Precision in Therapeutic Knowledge Portal (MPRINT-KP): Landscape Analysis of Pharmacology Research in Maternal and Pediatric Patient Populations.PMC12929201K12HD111057-03U01CA248240P30HD106451UM1TR004548T32GM008425R01LM014199Oteng SRLiu JSo GRogerson CMZhu ZJiang HOuyang JZhang SDeypalubos JAFWang LKirkpatrick LMLiu XBies RWei PO'Kane AGoodwin AAboshady OATillman EMCheng LZaidi SSGrannis SCostantine MChiang CWLi LShendre ALi SHuang YCao WQuinney SKMa HRahurkar SBartlett CfalseMaternal and Pediatric Precision in Therapeutic Knowledge Portal (MPRINT-KP): Landscape Analysis of Pharmacology Research in Maternal and Pediatric Patient Populations.Pregnant women and children have been underrepresented in clinical studies due to ethical concerns and perceived vulnerabilities. This resulted in a significant gap in knowledge regarding the safety and efficacy of medications for these populations. Maternal and Pediatric PRecision In Therapeutics Knowledge Portal (MPRINT-KP) is designed to provide a comprehensive view of pharmacokinetic, pharmaco-epidemiology, and clinical trial research evidence in maternal and pediatric patient populations. MPRINT-KP Silver was generated upon BioBERT models, due to their supreme performance in classifying pharmacokinetic, pharmaco-epidemiology, and clinical trial papers from PubMed, with an F1-score > 0.91. As of April 1, 2025, MPRINT-KP Silver contains 758,560 clinical pharmacology research papers in m2026-01-01T00:00:00Z2026 Mar2026-07-09T12:21:00.543Z2026-07-09T11:17:32.28ZS-EPMC129292014173079510.1002/phar.70096