biostudies-literatureHaider MREunice Kennedy Shriver National Institute of Child Health and Human DevelopmentNIDA NIH HHSNIMH NIH HHSNational Institute of Mental HealthNational Institute on Drug Abuse319-328https://www.ebi.ac.uk/biostudies/studies/S-EPMC12929244biostudies-literatureUnknown30(2)Georgia has one of the highest HIV diagnosis rates in the U.S., yet only 33% of Pre-Exposure Prophylaxis (PrEP) users in the Deep South live there. This study aims to determine the potential mediational role of internalized homonegativity and attitudes towards PrEP between gay community connectedness and PrEP use among men who have sex with men (MSM) living in Georgia. Participants (N = 121) completed an online survey in June 2020. PrEP use (yes/no) was defined by the question "the last time you had sex, were you taking PrEP, like Truvada?" The study also used the "8-item Identification and Involvement with the Gay Community scale", "9-item internalized homophobia scale", and a "3-item PrEP attitude scale". Path analysis was performed using Stata 17.0. After adjusting for sociodemographic AIDS and behaviorGay Community Connectedness, Internalized Homonegativity, and HIV Pre-Exposure Prophylaxis (PrEP) Attitudes and Use Among Men Who Have Sex with Men in Georgia: A Mediation Analysis.PMC12929244R34MH137775R01HD092185K01DA059329Haider MRKhan MSIGibbs JJSarwar GBrown MJWang LHansen NfalseGay Community Connectedness, Internalized Homonegativity, and HIV Pre-Exposure Prophylaxis (PrEP) Attitudes and Use Among Men Who Have Sex with Men in Georgia: A Mediation Analysis.Georgia has one of the highest HIV diagnosis rates in the U.S., yet only 33% of Pre-Exposure Prophylaxis (PrEP) users in the Deep South live there. This study aims to determine the potential mediational role of internalized homonegativity and attitudes towards PrEP between gay community connectedness and PrEP use among men who have sex with men (MSM) living in Georgia. Participants (N = 121) completed an online survey in June 2020. PrEP use (yes/no) was defined by the question "the last time you had sex, were you taking PrEP, like Truvada?" The study also used the "8-item Identification and Involvement with the Gay Community scale", "9-item internalized homophobia scale", and a "3-item PrEP attitude scale". Path analysis was performed using Stata 17.0. After adjusting for sociodemographic 2026-01-01T00:00:00Z2026 Feb2026-07-09T12:21:21.448Z2026-07-09T11:17:36.172ZS-EPMC129292444093848910.1007/s10461-025-04870-0