biostudies-literatureUnknown13Zhang L<h4>Background</h4>In patients with acute coronary syndrome (ACS), marital status may have a significant impact on the prognosis. However, it remains unclear whether marital status influences in-hospital mortality separately.<h4>Objective</h4>This study aims to examine the relationship between marital status and in-hospital mortality in ACS patients and to develop a predictive scoring system using a multivariable logistic regression model to evaluate marital status as an independent risk factor for in-hospital mortality.<h4>Methods</h4>We included 12,760 consecutive patients diagnosed with ACS during hospitalization. Patients were categorized into a death group or a survival group based on in-hospital outcomes, and further divided into married and non-married groups according to their mariFrontiers in cardiovascular medicine1611679https://www.ebi.ac.uk/biostudies/studies/S-EPMC12929463biostudies-literatureAssociation between marital status and in-hospital mortality in patients with acute coronary syndrome: a multivariable logistic regression analysis.PMC12929463Liu ZWu MZeng JZhang LPeng LJiang MZhou XPeng KfalseAssociation between marital status and in-hospital mortality in patients with acute coronary syndrome: a multivariable logistic regression analysis.<h4>Background</h4>In patients with acute coronary syndrome (ACS), marital status may have a significant impact on the prognosis. However, it remains unclear whether marital status influences in-hospital mortality separately.<h4>Objective</h4>This study aims to examine the relationship between marital status and in-hospital mortality in ACS patients and to develop a predictive scoring system using a multivariable logistic regression model to evaluate marital status as an independent risk factor for in-hospital mortality.<h4>Methods</h4>We included 12,760 consecutive patients diagnosed with ACS during hospitalization. Patients were categorized into a death group or a survival group based on in-hospital outcomes, and further divided into married and non-married groups according to their mari2026-01-01T00:00:00Z20262026-07-16T22:08:18.324Z2026-07-11T03:12:01.132ZS-EPMC129294634174396910.3389/fcvm.2026.1611679