{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["16(1)"],"submitter":["Lin JS"],"pubmed_abstract":["Given the complex relationship between cardiovascular disease (CVD) and chronic kidney disease (CKD), CVD-related markers may serve as CKD biomarkers. We examined associations of three major CVD-markers [mid-regional pro-adrenomedullin (MR-proADM), MR-pro-atrial natriuretic peptide (MR-proANP), and N-terminal pro-B-type natriuretic peptide (NT-proBNP)] with CKD. Cross-sectional analyses included up to 61,830 participants, and longitudinal analyses (NT-proBNP only) 4205 individuals. Kidney function was assessed by estimated glomerular filtration rate (eGFR) using creatinine, cystatin C, or both (eGFRcr-cys). Markers were categorized into four groups. Cross-sectional analyses found that higher levels of all three markers were consistently associated with lower eGFR and higher CKD prevalence."],"journal":["Scientific reports"],"pagination":["7488"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12929796"],"repository":["biostudies-literature"],"pubmed_title":["Longitudinal and cross-sectional associations of myocardial stress markers with kidney function and chronic kidney disease in the BiomarCaRE project."],"pmcid":["PMC12929796"],"pubmed_authors":["Zeller T","Kee F","Cesana G","Peters A","de Man Lapidoth J","Blankenberg S","Koenig W","Palmieri L","Salomaa V","Lorenz T","Lin JS","Donfrancesco C","Iacoviello L","Jousilahti P","Soderberg S","Tunstall-Pedoe H","Thorand B","Kuulasmaa K","De Ponti R"],"additional_accession":[]},"is_claimable":false,"name":"Longitudinal and cross-sectional associations of myocardial stress markers with kidney function and chronic kidney disease in the BiomarCaRE project.","description":"Given the complex relationship between cardiovascular disease (CVD) and chronic kidney disease (CKD), CVD-related markers may serve as CKD biomarkers. We examined associations of three major CVD-markers [mid-regional pro-adrenomedullin (MR-proADM), MR-pro-atrial natriuretic peptide (MR-proANP), and N-terminal pro-B-type natriuretic peptide (NT-proBNP)] with CKD. Cross-sectional analyses included up to 61,830 participants, and longitudinal analyses (NT-proBNP only) 4205 individuals. Kidney function was assessed by estimated glomerular filtration rate (eGFR) using creatinine, cystatin C, or both (eGFRcr-cys). Markers were categorized into four groups. Cross-sectional analyses found that higher levels of all three markers were consistently associated with lower eGFR and higher CKD prevalence.","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Feb","modification":"2026-07-09T12:21:43.336Z","creation":"2026-07-09T11:17:35.492Z"},"accession":"S-EPMC12929796","cross_references":{"pubmed":["41724744"],"doi":["10.1038/s41598-026-37377-2"]}}