biostudies-literatureUnknown27(7)Zhou J<h4>Objectives</h4>Emerging evidences have explored the association between famine exposure during early life and cancer risk in adulthood, but the results remain controversial and inconsistent. This study aimed to provide a comprehensive evidence on the relation of famine exposure to later cancer risk.<h4>Design</h4>Systematic review and meta-analysis.<h4>Methods</h4>Relevant reports published up to March, 2022 were identified by searching PubMed, Embase, Web of sciences and Medline databases. Pooled relative ratios (RRs) with 95% confidence intervals (CIs) were used to evaluate the effect famine exposure on cancer risk.<h4>Results</h4>Totally, 18 published articles with 6,061,147 subjects were included in this study. Compared with unexposed group, early life famine exposure dramatically The journal of nutrition, health & aging550-558https://www.ebi.ac.uk/biostudies/studies/S-EPMC12929998biostudies-literatureFamine Exposure during Early Life and Risk of Cancer in Adulthood: A Systematic Review and Meta-Analysis.PMC12929998Li SZuo ZLiu TDai YZhou JfalseFamine Exposure during Early Life and Risk of Cancer in Adulthood: A Systematic Review and Meta-Analysis.<h4>Objectives</h4>Emerging evidences have explored the association between famine exposure during early life and cancer risk in adulthood, but the results remain controversial and inconsistent. This study aimed to provide a comprehensive evidence on the relation of famine exposure to later cancer risk.<h4>Design</h4>Systematic review and meta-analysis.<h4>Methods</h4>Relevant reports published up to March, 2022 were identified by searching PubMed, Embase, Web of sciences and Medline databases. Pooled relative ratios (RRs) with 95% confidence intervals (CIs) were used to evaluate the effect famine exposure on cancer risk.<h4>Results</h4>Totally, 18 published articles with 6,061,147 subjects were included in this study. Compared with unexposed group, early life famine exposure dramatically 2023-01-01T00:00:00Z20232026-07-09T12:25:47.765Z2026-07-09T11:17:53.246ZS-EPMC129299983749810210.1007/s12603-023-1947-4