{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Kizito S"],"funding":["NICHD NIH HHS"],"pagination":["105753"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12930875"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["244"],"pubmed_abstract":["<h4>Objectives</h4>Adolescents living with HIV (ALHIV) have low viral suppression levels, with 1 in 3 ALHIV experiencing virologic failure, calling for more efforts to reverse these trends. We developed and validated a model that predicts the risk of virologic failure (VF) among ALHIV.<h4>Study design</h4>Cross-sectional study.<h4>Methods</h4>We used baseline data from 702 ALHIV enrolled in the Suubi + Adherence cluster-randomized clinical trial. Participants were aged 10-16 years, living with HIV and aware of their HIV status, and are living with a family. We developed a risk-prediction model for VF (viral load of ≥200 copies/mL) using sociodemographic, behavioral, psychological, economic, and treatment-related factors. LASSO logistic regression using 10-fold cross-validation with bootstr"],"journal":["Public health"],"pubmed_title":["A prediction model for virologic failure in adolescents living with HIV in Uganda: Findings from the Suubi+Adherence study."],"pmcid":["PMC12930875"],"funding_grant_id":["R01 HD074949"],"pubmed_authors":["Brownson R","Namatovu P","Nabayinda J","Johnson KJ","Ssewamala FM","Kizito S","Neilands TB","Nabunya P","McKay MM"],"additional_accession":[]},"is_claimable":false,"name":"A prediction model for virologic failure in adolescents living with HIV in Uganda: Findings from the Suubi+Adherence study.","description":"<h4>Objectives</h4>Adolescents living with HIV (ALHIV) have low viral suppression levels, with 1 in 3 ALHIV experiencing virologic failure, calling for more efforts to reverse these trends. We developed and validated a model that predicts the risk of virologic failure (VF) among ALHIV.<h4>Study design</h4>Cross-sectional study.<h4>Methods</h4>We used baseline data from 702 ALHIV enrolled in the Suubi + Adherence cluster-randomized clinical trial. Participants were aged 10-16 years, living with HIV and aware of their HIV status, and are living with a family. We developed a risk-prediction model for VF (viral load of ≥200 copies/mL) using sociodemographic, behavioral, psychological, economic, and treatment-related factors. LASSO logistic regression using 10-fold cross-validation with bootstr","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Jul","modification":"2026-07-09T12:23:48.239Z","creation":"2026-07-09T11:17:48.469Z"},"accession":"S-EPMC12930875","cross_references":{"pubmed":["40367622"],"doi":["10.1016/j.puhe.2025.105753"]}}