{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Marta-Enguita J"],"funding":["Instituto de Salud Carlos III","Sociedad Española de Neurología"],"pagination":["161"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12932306"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["273(2)"],"pubmed_abstract":["<h4>Background</h4>The left atrium (LA) and left atrial appendage (LAA) are common sites of thrombus formation leading to cardioembolic stroke. We aimed to include LA/LAA in acute-phase stroke CT angiography (CTA) to detect potential embolic sources early.<h4>Methods</h4>The CTA scan range was extended to include the LA/LAA. We retrospectively reviewed CTAs from patients treated at Donostia University Hospital between December 2020 and November 2021. LA/LAA images were classified as normal filling, non-well-defined filling defect, and thrombus-suggestive filling defect. Clinical, demographic, and stroke severity data were compared across groups.<h4>Results</h4>Among 299 patients included, 6 (2%) had thrombus-suggestive filling defects, and 32 (11%) had non-well-defined defects. Both groups"],"journal":["Journal of neurology"],"pubmed_title":["Extended CTA scan range for early detection of left atrial and left atrial appendage thrombus and other filling defects in acute ischemic stroke."],"pmcid":["PMC12932306"],"funding_grant_id":["RICORS-Ictus RD24/0009/0023","PUBLIbeCAs 2022"],"pubmed_authors":["Vasquez-Ferreccio S","Biain S","Gomez-Usabiaga V","Diez N","Equiza J","de Arce A","Martinez-Zabaleta M","Ayuso D","Marta-Enguita J","de la Riva P","Gonzalez F","Del Bosque C","Arenaza G"],"additional_accession":[]},"is_claimable":false,"name":"Extended CTA scan range for early detection of left atrial and left atrial appendage thrombus and other filling defects in acute ischemic stroke.","description":"<h4>Background</h4>The left atrium (LA) and left atrial appendage (LAA) are common sites of thrombus formation leading to cardioembolic stroke. We aimed to include LA/LAA in acute-phase stroke CT angiography (CTA) to detect potential embolic sources early.<h4>Methods</h4>The CTA scan range was extended to include the LA/LAA. We retrospectively reviewed CTAs from patients treated at Donostia University Hospital between December 2020 and November 2021. LA/LAA images were classified as normal filling, non-well-defined filling defect, and thrombus-suggestive filling defect. Clinical, demographic, and stroke severity data were compared across groups.<h4>Results</h4>Among 299 patients included, 6 (2%) had thrombus-suggestive filling defects, and 32 (11%) had non-well-defined defects. Both groups","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Feb","modification":"2026-07-16T21:28:37.27Z","creation":"2026-07-10T03:15:34.435Z"},"accession":"S-EPMC12932306","cross_references":{"pubmed":["41733714"],"doi":["10.1007/s00415-026-13692-6"]}}