{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["131(2)"],"submitter":["Kendrick J"],"funding":["Department of Health, Government of Western Australia"],"pubmed_abstract":["<h4>Objectives</h4>The primary aim of this study was to quantify the subject-level test-retest repeatability of artificial intelligence (AI)-derived PSMA PET imaging biomarkers using a previously developed model. The secondary aim was to assess the performance of this segmentation model, which was trained on [<sup>68</sup> Ga]Ga-PSMA-11 PET scans, on [<sup>18</sup>F]F-PSMA-1007 PET scans.<h4>Methods</h4>This was a post-hoc analysis of a prospective, single-center, test-retest trial. Seventeen patients with metastatic prostate cancer (mPCa) were randomised into groups, either receiving the same tracer ([<sup>68</sup> Ga]Ga-PSMA-11 or [<sup>18</sup>F]F-PSMA-1007) for both scans (intra-tracer group, n = 9) or a different tracer (inter-tracer group, n = 8). Scans were delineated using a fully "],"journal":["La Radiologia medica"],"pagination":["320-331"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12932408"],"repository":["biostudies-literature"],"pubmed_title":["Deep learning-based PSMA PET segmentation repeatability: A post-hoc analysis of a single-center, prospective, test-retest trial."],"pmcid":["PMC12932408"],"pubmed_authors":["Ebert MA","Hassan GM","Barry N","Ong JSL","Jeraj R","Kendrick J","Francis RJ"],"additional_accession":[]},"is_claimable":false,"name":"Deep learning-based PSMA PET segmentation repeatability: A post-hoc analysis of a single-center, prospective, test-retest trial.","description":"<h4>Objectives</h4>The primary aim of this study was to quantify the subject-level test-retest repeatability of artificial intelligence (AI)-derived PSMA PET imaging biomarkers using a previously developed model. The secondary aim was to assess the performance of this segmentation model, which was trained on [<sup>68</sup> Ga]Ga-PSMA-11 PET scans, on [<sup>18</sup>F]F-PSMA-1007 PET scans.<h4>Methods</h4>This was a post-hoc analysis of a prospective, single-center, test-retest trial. Seventeen patients with metastatic prostate cancer (mPCa) were randomised into groups, either receiving the same tracer ([<sup>68</sup> Ga]Ga-PSMA-11 or [<sup>18</sup>F]F-PSMA-1007) for both scans (intra-tracer group, n = 9) or a different tracer (inter-tracer group, n = 8). Scans were delineated using a fully ","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Feb","modification":"2026-07-16T21:32:44.165Z","creation":"2026-07-10T03:16:28.009Z"},"accession":"S-EPMC12932408","cross_references":{"pubmed":["41166032"],"doi":["10.1007/s11547-025-02137-1"]}}