{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["16(12)"],"submitter":["Rahman MR"],"pubmed_abstract":["Optimising continuous phototrophic cultivation remains a major challenge for scalable, energy-efficient cyanobacterial bioprocesses. Here, we combine controlled photophysiology, long-term continuous experimentation, multi-parameter analysis, and batch-derived Monod kinetic modelling to define a precise operational window for <i>Synechocystis</i> sp. PCC 6803 under flat-plate photobioreactor (FP-PBR) illumination. Using a fully calibrated FP-PBR platform, we first quantified intrinsic growth limits (<i>µ</i> <sub>max</sub> = 0.081-0.118 day<sup>-1</sup>) across low, moderate, and high irradiance regimes, establishing the illumination-driven growth ceilings that constrain downstream continuous operation. Guided by these kinetic boundaries, continuous cultivation demonstrated that productive "],"journal":["RSC advances"],"pagination":["11036-11048"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12933868"],"repository":["biostudies-literature"],"pubmed_title":["Photonic-chemostat engineering for efficient continuous cultivation of cyanobacteria."],"pmcid":["PMC12933868"],"pubmed_authors":["Hellgardt K","Rahman MR","Noori MT"],"additional_accession":[]},"is_claimable":false,"name":"Photonic-chemostat engineering for efficient continuous cultivation of cyanobacteria.","description":"Optimising continuous phototrophic cultivation remains a major challenge for scalable, energy-efficient cyanobacterial bioprocesses. Here, we combine controlled photophysiology, long-term continuous experimentation, multi-parameter analysis, and batch-derived Monod kinetic modelling to define a precise operational window for <i>Synechocystis</i> sp. PCC 6803 under flat-plate photobioreactor (FP-PBR) illumination. Using a fully calibrated FP-PBR platform, we first quantified intrinsic growth limits (<i>µ</i> <sub>max</sub> = 0.081-0.118 day<sup>-1</sup>) across low, moderate, and high irradiance regimes, establishing the illumination-driven growth ceilings that constrain downstream continuous operation. Guided by these kinetic boundaries, continuous cultivation demonstrated that productive ","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Feb","modification":"2026-07-16T22:29:29.627Z","creation":"2026-07-11T03:12:16.818Z"},"accession":"S-EPMC12933868","cross_references":{"pubmed":["41757307"],"doi":["10.1039/d5ra09945e"]}}