{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["25(3)"],"submitter":["Tang Y"],"pubmed_abstract":["<h4>Objective</h4>To evaluate the effectiveness of high-frequency microneedling (HFM) using a layering technique versus conventional HFM for facial rejuvenation, with the Fitzpatrick Wrinkle and Laxity Classification Scale (FWCS) score at 3 months post-treatment as the primary endpoint.<h4>Methods</h4>A prospective non-randomized controlled study was conducted on 30 patients undergoing facial rejuvenation at Changzhou TCM Hospital (January-December 2024), who were divided into two groups (n = 15 each). The conventional group received standard HFM, while the layered group received HFM with needle length, power, and pulse width adjusted for superficial, middle, and deep skin layers. The primary endpoint was the Fitzpatrick Wrinkle and Laxity Classification Scale (FWCS) score at 3 months post"],"journal":["Journal of cosmetic dermatology"],"pagination":["e70651"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12936247"],"repository":["biostudies-literature"],"pubmed_title":["Comparative Evaluation of High-Frequency Microneedling Using a Layering Technique Versus Conventional Technique for Facial Rejuvenation."],"pmcid":["PMC12936247"],"pubmed_authors":["Wu K","Lu Z","Fan M","Song X","Tang Y","Qiao M"],"additional_accession":[]},"is_claimable":false,"name":"Comparative Evaluation of High-Frequency Microneedling Using a Layering Technique Versus Conventional Technique for Facial Rejuvenation.","description":"<h4>Objective</h4>To evaluate the effectiveness of high-frequency microneedling (HFM) using a layering technique versus conventional HFM for facial rejuvenation, with the Fitzpatrick Wrinkle and Laxity Classification Scale (FWCS) score at 3 months post-treatment as the primary endpoint.<h4>Methods</h4>A prospective non-randomized controlled study was conducted on 30 patients undergoing facial rejuvenation at Changzhou TCM Hospital (January-December 2024), who were divided into two groups (n = 15 each). The conventional group received standard HFM, while the layered group received HFM with needle length, power, and pulse width adjusted for superficial, middle, and deep skin layers. The primary endpoint was the Fitzpatrick Wrinkle and Laxity Classification Scale (FWCS) score at 3 months post","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Mar","modification":"2026-07-16T21:58:33.997Z","creation":"2026-07-11T03:08:59.79Z"},"accession":"S-EPMC12936247","cross_references":{"pubmed":["41742263"],"doi":["10.1111/jocd.70651"]}}