biostudies-literatureSriburin SNational Science, Research and Innovation Fund (NSRF), ThailandKhon Kaen University316https://www.ebi.ac.uk/biostudies/studies/S-EPMC12938135biostudies-literatureUnknown15(4)The venom of the Asian hornet (<i>Vespa affinis</i>) comprises a complex mixture of biologically active substances, including various enzymes such as phospholipase A and hyaluronidase; amines such as histamine, serotonin, and catecholamines; peptides such as mastoparan and vespakinin; and other components including acetylcholine and antigen 5. This complexity reflects the highly evolved nature of <i>V. affinis</i> as a venomous insect. The composition of animal venoms often exhibits a certain degree of variability, making the study of biogenic amines particularly intriguing. The objective of this research was to confirm and identify the presence of tetradecylamine in the venom of <i>Vespa affinis</i> using the scientific computational analysis software MetFrag. In addition, the study aimedBiologyTetradecylamine: A Newly Identified Biogenic Amine Compound from the Venom of <i>Vespa affinis</i>.PMC12938135NoChaveerach AShinsuphan NSaengkun YKulchat SPatramanon RJanpan PDaduang JAreemit JSriburin SKlamrak AJangpromma NDaduang SfalseTetradecylamine: A Newly Identified Biogenic Amine Compound from the Venom of <i>Vespa affinis</i>.The venom of the Asian hornet (<i>Vespa affinis</i>) comprises a complex mixture of biologically active substances, including various enzymes such as phospholipase A and hyaluronidase; amines such as histamine, serotonin, and catecholamines; peptides such as mastoparan and vespakinin; and other components including acetylcholine and antigen 5. This complexity reflects the highly evolved nature of <i>V. affinis</i> as a venomous insect. The composition of animal venoms often exhibits a certain degree of variability, making the study of biogenic amines particularly intriguing. The objective of this research was to confirm and identify the presence of tetradecylamine in the venom of <i>Vespa affinis</i> using the scientific computational analysis software MetFrag. In addition, the study aimed2026-01-01T00:00:00Z2026 Feb2026-07-11T03:17:58.379Z2026-07-11T03:12:03.472ZS-EPMC129381354174462510.3390/biology15040316