{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["48(2)"],"submitter":["Torres Flores C"],"pubmed_abstract":["<i>Flaveria trinervia</i> (Spreng) C. Mohr is a plant traditionally used in Mexican medicine. In this study, gas chromatography-mass spectrometry (GC-MS) combined with network pharmacology was employed to characterize volatile and semi-volatile metabolites from <i>F. trinervia</i> leaves and to explore their potential system-level mechanisms of action in inflammatory and tumor-related disorders. A dual extraction strategy (hexane/dichloromethane and acetone/chloroform) was applied, followed by GC-MS-based compound identification. Putative molecular targets were predicted using established pharmacological databases, and protein-protein interaction networks were constructed to identify topological features and enriched biological pathways. A total of 11 bioactive compounds were tentatively i"],"journal":["Current issues in molecular biology"],"pagination":["160"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12939618"],"repository":["biostudies-literature"],"pubmed_title":["From Gas Chromatography-Mass Spectrometry (GC-MS) to Network Pharmacology: System-Level Insights into the Multi-Target Biological Potential of &lt;i&gt;Flaveria trinervia&lt;/i&gt; (Spreng.) C. Mohr."],"pmcid":["PMC12939618"],"pubmed_authors":["Mora Guzman Z","Torres Flores C","Lastre-Dominguez CM","Jarquin Gonzalez EE","Perez-Campos E","Lopez Montesinos KC","Laguna-Barrios LA","Martinez Cruz M","Perez-Campos Mayoral L","Mendez-Rodriguez KB","Perez-Vazquez FJ","Perez Campos-Mayoral E","Hernandez-Huerta MT","Cabrera-Fuentes HA","Pina Canseco MDS"],"additional_accession":[]},"is_claimable":false,"name":"From Gas Chromatography-Mass Spectrometry (GC-MS) to Network Pharmacology: System-Level Insights into the Multi-Target Biological Potential of &lt;i&gt;Flaveria trinervia&lt;/i&gt; (Spreng.) C. Mohr.","description":"<i>Flaveria trinervia</i> (Spreng) C. Mohr is a plant traditionally used in Mexican medicine. In this study, gas chromatography-mass spectrometry (GC-MS) combined with network pharmacology was employed to characterize volatile and semi-volatile metabolites from <i>F. trinervia</i> leaves and to explore their potential system-level mechanisms of action in inflammatory and tumor-related disorders. A dual extraction strategy (hexane/dichloromethane and acetone/chloroform) was applied, followed by GC-MS-based compound identification. Putative molecular targets were predicted using established pharmacological databases, and protein-protein interaction networks were constructed to identify topological features and enriched biological pathways. A total of 11 bioactive compounds were tentatively i","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Feb","modification":"2026-07-11T03:17:52.235Z","creation":"2026-07-11T03:09:33.027Z"},"accession":"S-EPMC12939618","cross_references":{"pubmed":["41751423"],"doi":["10.3390/cimb48020160"]}}