{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Morato-Cecchini C"],"funding":["Ministerio de Ciencia, Innovación y Universidades","Gobierno del Principado de Asturias","Fundación Caja Rural de Asturias"],"pagination":["137"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12940588"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["12(2)"],"pubmed_abstract":["The development of photocurable hydrogel biomaterial inks with suitable rheology, low cytotoxicity, and tuneable mechanical properties is essential for reliable biofabrication. This study aimed to formulate PEGDA-gelatine-collagen inks using lithium phenyl-2,4,6-trimethylbenzoylphosphinate (LAP) as photoinitiator. Rheological characterisation and flow-model fitting were performed, mechanical stiffness modulation under different light intensities was evaluated, complex structures were printed using direct extrusion and FRESH methodologies, and PEGDA/LAP extractables were quantified by NMR after controlled washing procedures. In vitro assays assessed cell viability and proliferation on the resulting scaffolds. The Herschel-Bulkley model best described the flow behaviour across formulations; "],"journal":["Gels (Basel, Switzerland)"],"pubmed_title":["Comprehensive Characterisation of Photocurable PEGDA/Gelatine Hydrogels for Extrusion-Based 3D Printing."],"pmcid":["PMC12940588"],"funding_grant_id":["CER-20231013","Beca FCRA","PID2022-140635NB-I00","IDE/2024/000932"],"pubmed_authors":["Herrada-Manchon H","Morato-Cecchini C","Celada L","Fernandez MA","Aguilar E","Sanchez-Suarez L","Rodriguez-Gonzalez D"],"additional_accession":[]},"is_claimable":false,"name":"Comprehensive Characterisation of Photocurable PEGDA/Gelatine Hydrogels for Extrusion-Based 3D Printing.","description":"The development of photocurable hydrogel biomaterial inks with suitable rheology, low cytotoxicity, and tuneable mechanical properties is essential for reliable biofabrication. This study aimed to formulate PEGDA-gelatine-collagen inks using lithium phenyl-2,4,6-trimethylbenzoylphosphinate (LAP) as photoinitiator. Rheological characterisation and flow-model fitting were performed, mechanical stiffness modulation under different light intensities was evaluated, complex structures were printed using direct extrusion and FRESH methodologies, and PEGDA/LAP extractables were quantified by NMR after controlled washing procedures. In vitro assays assessed cell viability and proliferation on the resulting scaffolds. The Herschel-Bulkley model best described the flow behaviour across formulations; ","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Feb","modification":"2026-07-11T03:19:49.922Z","creation":"2026-07-11T03:12:07.932Z"},"accession":"S-EPMC12940588","cross_references":{"pubmed":["41745009"],"doi":["10.3390/gels12020137"]}}