{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Franco-Vasquez AM"],"funding":["SECIHTI","PAPIIT-UNAM","CONAHCyT PRONAII"],"pagination":["e0014021"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12945309"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["20(2)"],"pubmed_abstract":["<h4>Background</h4>In Colombia, Lachesis snakes are not commonly implicated in snakebite incidents. However, the considerable number of severe envenomation cases and associated mortality rates represent a significant challenge that must be overcome. A deeper comprehension of the composition of their venom, along with its variability across their distribution range, including ontogenetic and sexual variations, will contribute to the enhancement of the scarce knowledge about them and the mitigation of the consequences of snake envenomation.<h4>Methodology/principal findings</h4>Through the application of snake venomics and in conjunction with biochemical characterization, here we analyze the venoms of fourteen specimens of Lachesis acrochorda (adults and juveniles) and L. muta from several g"],"journal":["PLoS neglected tropical diseases"],"pubmed_title":["Comparative venomics reveals intra, interspecific and ontogenetic changes in the venom composition of Lachesis snakes from Colombia."],"pmcid":["PMC12945309"],"funding_grant_id":["IN215823","1011003","303045"],"pubmed_authors":["Melendez-Martinez D","Mejia-Sanchez MA","Lazcano-Perez F","Arreguin-Espinosa R","Corzo G","Carbajal-Saucedo A","Franco-Vasquez AM"],"additional_accession":[]},"is_claimable":false,"name":"Comparative venomics reveals intra, interspecific and ontogenetic changes in the venom composition of Lachesis snakes from Colombia.","description":"<h4>Background</h4>In Colombia, Lachesis snakes are not commonly implicated in snakebite incidents. However, the considerable number of severe envenomation cases and associated mortality rates represent a significant challenge that must be overcome. A deeper comprehension of the composition of their venom, along with its variability across their distribution range, including ontogenetic and sexual variations, will contribute to the enhancement of the scarce knowledge about them and the mitigation of the consequences of snake envenomation.<h4>Methodology/principal findings</h4>Through the application of snake venomics and in conjunction with biochemical characterization, here we analyze the venoms of fourteen specimens of Lachesis acrochorda (adults and juveniles) and L. muta from several g","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Feb","modification":"2026-07-11T03:11:07.26Z","creation":"2026-07-11T03:08:55.326Z"},"accession":"S-EPMC12945309","cross_references":{"pubmed":["41729992"],"doi":["10.1371/journal.pntd.0014021"]}}