{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["26(1)"],"submitter":["Miki K"],"funding":["A Grant-in-Aid for Clinical Research from the National Hospital Organization"],"pubmed_abstract":["<h4>Background</h4>Oxygen uptake (V'<sub>O2</sub>) obtained from expiratory gas analysis is generally calculated using minute ventilation (V'<sub>E</sub>) and the inspired‒expired mean oxygen (O<sub>2</sub>) concentration difference (ΔF<sub>O2</sub>) during cardiopulmonary exercise testing (CPET). We have reported that ΔF<sub>O2</sub>, which is associated with ventilatory efficiency, is independent of V'<sub>E</sub> at peak exercise and affects exercise tolerance in respiratory diseases other than idiopathic pulmonary fibrosis (IPF). We hypothesized that similar results are obtained in IPF, and that ΔF<sub>O2</sub> is a prognostic factor for survival in IPF.<h4>Methods</h4>Forty-three patients with IPF, who underwent CPET with blood gas analysis were enrolled from our database.<h4>Results<"],"journal":["BMC pulmonary medicine"],"pagination":["102"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12947475"],"repository":["biostudies-literature"],"pubmed_title":["Exercise alveolar oxygen extraction rate reflects ventilatory efficiency and predicts outcomes in idiopathic pulmonary fibrosis."],"pmcid":["PMC12947475"],"pubmed_authors":["Tsujino K","Kida H","Miki K","Nagata Y","Mihashi Y","Nishijima R","Sugisawa K","Nii T","Matsuki T"],"additional_accession":[]},"is_claimable":false,"name":"Exercise alveolar oxygen extraction rate reflects ventilatory efficiency and predicts outcomes in idiopathic pulmonary fibrosis.","description":"<h4>Background</h4>Oxygen uptake (V'<sub>O2</sub>) obtained from expiratory gas analysis is generally calculated using minute ventilation (V'<sub>E</sub>) and the inspired‒expired mean oxygen (O<sub>2</sub>) concentration difference (ΔF<sub>O2</sub>) during cardiopulmonary exercise testing (CPET). We have reported that ΔF<sub>O2</sub>, which is associated with ventilatory efficiency, is independent of V'<sub>E</sub> at peak exercise and affects exercise tolerance in respiratory diseases other than idiopathic pulmonary fibrosis (IPF). We hypothesized that similar results are obtained in IPF, and that ΔF<sub>O2</sub> is a prognostic factor for survival in IPF.<h4>Methods</h4>Forty-three patients with IPF, who underwent CPET with blood gas analysis were enrolled from our database.<h4>Results<","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Dec","modification":"2026-07-16T22:25:03.022Z","creation":"2026-07-11T03:12:00.906Z"},"accession":"S-EPMC12947475","cross_references":{"pubmed":["41413882"],"doi":["10.1186/s12890-025-04064-3"]}}