biostudies-literatureKoren RMinistry of Innovation, Science and Technology and the Ministry of HealthTel Aviv University141-151https://www.ebi.ac.uk/biostudies/studies/S-EPMC12948814biostudies-literatureUnknown21(1)While sex differences in type 2 diabetes mellitus (T2DM) are well-documented in outpatient settings, data on inpatient disparities remain limited. This study examines the relationship between sex and glycemic control, chronic treatment patterns, and hospitalization outcomes in patients with T2DM. A historical cohort of 5,133 adult T2DM patients hospitalized for > 24 h at a tertiary Israeli medical center in 2023 was analyzed. Outcomes included hypoglycemia, hyperglycemia, length of stay, 30-day readmission, and mortality. Propensity score matching and multivariable regression were applied to adjust for confounding variables. Men were more frequently treated with chronic aspirin therapy than women (35.8% vs. 29.4%; p < 0.001), a difference that remained significant after multivariable adjusInternal and emergency medicineSex based disparities in glycemic control and hospitalization outcomes of medical patients with diabetes mellitus-a historical cohort study.PMC129488140006865Elkan MZiv-Baran TBarouch AKoren RfalseSex based disparities in glycemic control and hospitalization outcomes of medical patients with diabetes mellitus-a historical cohort study.While sex differences in type 2 diabetes mellitus (T2DM) are well-documented in outpatient settings, data on inpatient disparities remain limited. This study examines the relationship between sex and glycemic control, chronic treatment patterns, and hospitalization outcomes in patients with T2DM. A historical cohort of 5,133 adult T2DM patients hospitalized for > 24 h at a tertiary Israeli medical center in 2023 was analyzed. Outcomes included hypoglycemia, hyperglycemia, length of stay, 30-day readmission, and mortality. Propensity score matching and multivariable regression were applied to adjust for confounding variables. Men were more frequently treated with chronic aspirin therapy than women (35.8% vs. 29.4%; p < 0.001), a difference that remained significant after multivariable adjus2026-01-01T00:00:00Z2026 Jan2026-07-16T23:36:09.581Z2026-07-12T03:11:24.879ZS-EPMC129488144117527610.1007/s11739-025-04170-4