{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Fink JL"],"funding":["NIDDK NIH HHS"],"pagination":["D213-7"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC1347432"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["34(Database issue)"],"pubmed_abstract":["We present here LOCATE, a curated, web-accessible database that houses data describing the membrane organization and subcellular localization of proteins from the FANTOM3 Isoform Protein Sequence set. Membrane organization is predicted by the high-throughput, computational pipeline MemO. The subcellular locations of selected proteins from this set were determined by a high-throughput, immunofluorescence-based assay and by manually reviewing >1700 peer-reviewed publications. LOCATE represents the first effort to catalogue the experimentally verified subcellular location and membrane organization of mammalian proteins using a high-throughput approach and provides localization data for approximately 40% of the mouse proteome. It is available at http://locate.imb.uq.edu.au."],"journal":["Nucleic acids research"],"pubmed_title":["LOCATE: a mouse protein subcellular localization database."],"pmcid":["PMC1347432"],"funding_grant_id":["DK63400","R01 DK063400"],"pubmed_authors":["Zhang F","Fink JL","Teasdale MS","Hayashizaki Y","Hanson K","Carninci P","Teasdale RD","Kawai J","Kai C","Aturaliya RN","Davis MJ"],"additional_accession":[]},"is_claimable":false,"name":"LOCATE: a mouse protein subcellular localization database.","description":"We present here LOCATE, a curated, web-accessible database that houses data describing the membrane organization and subcellular localization of proteins from the FANTOM3 Isoform Protein Sequence set. Membrane organization is predicted by the high-throughput, computational pipeline MemO. The subcellular locations of selected proteins from this set were determined by a high-throughput, immunofluorescence-based assay and by manually reviewing >1700 peer-reviewed publications. LOCATE represents the first effort to catalogue the experimentally verified subcellular location and membrane organization of mammalian proteins using a high-throughput approach and provides localization data for approximately 40% of the mouse proteome. It is available at http://locate.imb.uq.edu.au.","dates":{"release":"2006-01-01T00:00:00Z","publication":"2006 Jan","modification":"2026-03-16T16:15:05.97Z","creation":"2019-03-27T01:25:50Z"},"accession":"S-EPMC1347432","cross_references":{"pubmed":["16381849"],"doi":["10.1093/nar/gkj069"]}}