{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["DeCarlo AA"],"funding":["NIDCR NIH HHS"],"pagination":["562-6"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC143394"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["71(1)"],"pubmed_abstract":["In a rat periodontitis model, preinoculation with the Porphyromonas gingivalis HA2 binding domain for hemoglobin provided protection from disease. Protection was associated with induced anti-HA2 immunoglobulin G (IgG) humoral antibodies. The IgG subclass ratios suggested that relatively lower Th2/Th1-driven responses were directly associated with protection when rHA2 was administered in saline."],"journal":["Infection and immunity"],"pubmed_title":["Feasibility of an HA2 domain-based periodontitis vaccine."],"pmcid":["PMC143394"],"funding_grant_id":["R43DE14013-01"],"pubmed_authors":["DeCarlo AA","Huang Y","Collyer CA","Langley DB","Katz J"],"additional_accession":[]},"is_claimable":false,"name":"Feasibility of an HA2 domain-based periodontitis vaccine.","description":"In a rat periodontitis model, preinoculation with the Porphyromonas gingivalis HA2 binding domain for hemoglobin provided protection from disease. Protection was associated with induced anti-HA2 immunoglobulin G (IgG) humoral antibodies. The IgG subclass ratios suggested that relatively lower Th2/Th1-driven responses were directly associated with protection when rHA2 was administered in saline.","dates":{"release":"2003-01-01T00:00:00Z","publication":"2003 Jan","modification":"2025-04-21T15:30:03.894Z","creation":"2019-03-27T00:17:33Z"},"accession":"S-EPMC143394","cross_references":{"pubmed":["12496212"],"doi":["10.1128/IAI.71.1.562-566.2003","10.1128/iai.71.1.562-566.2003"]}}