{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["173(3)"],"submitter":["Sun X"],"pubmed_abstract":["Neuronal-glial communication is essential for constructing the orthogonal axon scaffold in the developing Drosophila central nervous system (CNS). Longitudinal glia (LG) guide extending commissural and longitudinal axons while pioneer and commissural neurons maintain glial survival and positioning. However, the transcriptional regulatory mechanisms controlling these processes are not known. Previous studies showed that the midline function of the jing C2H2-type zinc-finger transcription factor was only partially required for axon scaffold formation in the Drosophila CNS. We therefore screened for gain-of-function enhancers of jing gain of function in the eye and identified the Drosophila homolog of the disease gene of human alpha-thalassemia/mental retardation X-linked (ATR-X) as well as o"],"journal":["Genetics"],"pagination":["1397-415"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC1526706"],"repository":["biostudies-literature"],"pubmed_title":["Glial and neuronal functions of the Drosophila homolog of the human SWI/SNF gene ATR-X (DATR-X) and the jing zinc-finger gene specify the lateral positioning of longitudinal glia and axons."],"pmcid":["PMC1526706"],"pubmed_authors":["Sonnenfeld M","Sun X","Morozova T"],"additional_accession":[]},"is_claimable":false,"name":"Glial and neuronal functions of the Drosophila homolog of the human SWI/SNF gene ATR-X (DATR-X) and the jing zinc-finger gene specify the lateral positioning of longitudinal glia and axons.","description":"Neuronal-glial communication is essential for constructing the orthogonal axon scaffold in the developing Drosophila central nervous system (CNS). Longitudinal glia (LG) guide extending commissural and longitudinal axons while pioneer and commissural neurons maintain glial survival and positioning. However, the transcriptional regulatory mechanisms controlling these processes are not known. Previous studies showed that the midline function of the jing C2H2-type zinc-finger transcription factor was only partially required for axon scaffold formation in the Drosophila CNS. We therefore screened for gain-of-function enhancers of jing gain of function in the eye and identified the Drosophila homolog of the disease gene of human alpha-thalassemia/mental retardation X-linked (ATR-X) as well as o","dates":{"release":"2006-01-01T00:00:00Z","publication":"2006 Jul","modification":"2025-04-19T00:07:17.847Z","creation":"2019-10-26T12:53:10Z"},"accession":"S-EPMC1526706","cross_references":{"pubmed":["16648585"],"doi":["10.1534/genetics.106.057893"]}}