biostudies-literatureUnknown31(7)Mannhaupt GThe German Neurospora Genome Project has assembled sequences from ordered cosmid and BAC clones of linkage groups II and V of the genome of Neurospora crassa in 13 and 12 contigs, respectively. Including additional sequences located on other linkage groups a total of 12 Mb were subjected to a manual gene extraction and annotation process. The genome comprises a small number of repetitive elements, a low degree of segmental duplications and very few paralogous genes. The analysis of the 3218 identified open reading frames provides a first overview of the protein equipment of a filamentous fungus. Significantly, N.crassa possesses a large variety of metabolic enzymes including a substantial number of enzymes involved in the degradation of complex substrates as well as secondary metabolism. WNucleic acids research1944-54https://www.ebi.ac.uk/biostudies/studies/S-EPMC152809biostudies-literatureWhat's in the genome of a filamentous fungus? Analysis of the Neurospora genome sequence.PMC152809Montrone CKempken FMaier JFartmann BMewes HWAign VNyakatura GMannhaupt GHaase DSchulte UHoheisel JDfalseWhat's in the genome of a filamentous fungus? Analysis of the Neurospora genome sequence.The German Neurospora Genome Project has assembled sequences from ordered cosmid and BAC clones of linkage groups II and V of the genome of Neurospora crassa in 13 and 12 contigs, respectively. Including additional sequences located on other linkage groups a total of 12 Mb were subjected to a manual gene extraction and annotation process. The genome comprises a small number of repetitive elements, a low degree of segmental duplications and very few paralogous genes. The analysis of the 3218 identified open reading frames provides a first overview of the protein equipment of a filamentous fungus. Significantly, N.crassa possesses a large variety of metabolic enzymes including a substantial number of enzymes involved in the degradation of complex substrates as well as secondary metabolism. W2003-01-01T00:00:00Z2003 Apr2026-05-05T04:02:58.11Z2026-04-07T21:22:00.86ZS-EPMC1528091265501110.1093/nar/gkg293