{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["76(5)"],"submitter":["Wu T"],"pubmed_abstract":["Mice contain a serum factor capable of inactivating some subgroups of murine leukemia viruses. This leukemia virus-inactivating factor (LVIF) is distinct from immunoglobulin and complement; it has been associated with lipoprotein serum fractions and may be an apolipoprotein. The present study demonstrates that some Swiss-derived inbred strains are LVIF negative. Genetic crosses show this factor to be under control of a single gene that maps to distal chromosome 10 at or near the gene encoding a minor serum apolipoprotein, apolipoprotein F (ApoF). To evaluate this gene as a potential candidate for LVIF, the mouse ApoF gene was cloned and sequenced and its expression was assessed in LVIF-positive and -negative mice; no obvious differences were detected, suggesting that LVIF is under the cont"],"journal":["Journal of virology"],"pagination":["2279-86"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC153798"],"repository":["biostudies-literature"],"pubmed_title":["Genetic control of a mouse serum lipoprotein factor that inactivates murine leukemia viruses: evaluation of apolipoprotein F as a candidate."],"pmcid":["PMC153798"],"pubmed_authors":["Lee CG","Buckler-White A","Wu T","Kozak CA"],"additional_accession":[]},"is_claimable":false,"name":"Genetic control of a mouse serum lipoprotein factor that inactivates murine leukemia viruses: evaluation of apolipoprotein F as a candidate.","description":"Mice contain a serum factor capable of inactivating some subgroups of murine leukemia viruses. This leukemia virus-inactivating factor (LVIF) is distinct from immunoglobulin and complement; it has been associated with lipoprotein serum fractions and may be an apolipoprotein. The present study demonstrates that some Swiss-derived inbred strains are LVIF negative. Genetic crosses show this factor to be under control of a single gene that maps to distal chromosome 10 at or near the gene encoding a minor serum apolipoprotein, apolipoprotein F (ApoF). To evaluate this gene as a potential candidate for LVIF, the mouse ApoF gene was cloned and sequenced and its expression was assessed in LVIF-positive and -negative mice; no obvious differences were detected, suggesting that LVIF is under the cont","dates":{"release":"2002-01-01T00:00:00Z","publication":"2002 Mar","modification":"2025-04-05T15:31:15.016Z","creation":"2019-03-27T00:17:43Z"},"accession":"S-EPMC153798","cross_references":{"pubmed":["11836406"],"doi":["10.1128/jvi.76.5.2279-2286.2002"]}}