biostudies-literatureUnknown44(9)Mathet VLGenotype E hepatitis B virus (HBV) was detected in two Argentine sisters exhibiting an African mitochondrial lineage. One of them (who had been vaccinated against HBV) exhibited anti-HBs cocirculating antibodies without HBsAg escape mutants, while her unvaccinated sister showed a D144A HBsAg escape mutant without anti-HBs antibodies. Both sisters carried an unusual L209V substitution within HBsAg.Journal of clinical microbiology3435-9https://www.ebi.ac.uk/biostudies/studies/S-EPMC1594728biostudies-literatureDetection of hepatitis B virus (HBV) genotype E carried--even in the presence of high titers of anti-HBs antibodies--by an Argentinean patient of African descent who had received vaccination against HBV.PMC1594728Daleoso GTrinks JLibellara BCorach DRuiz VLeon LMMathet VLCuestas MLRivero COubina JRMinassian MLSala AfalseDetection of hepatitis B virus (HBV) genotype E carried--even in the presence of high titers of anti-HBs antibodies--by an Argentinean patient of African descent who had received vaccination against HBV.Genotype E hepatitis B virus (HBV) was detected in two Argentine sisters exhibiting an African mitochondrial lineage. One of them (who had been vaccinated against HBV) exhibited anti-HBs cocirculating antibodies without HBsAg escape mutants, while her unvaccinated sister showed a D144A HBsAg escape mutant without anti-HBs antibodies. Both sisters carried an unusual L209V substitution within HBsAg.2006-01-01T00:00:00Z2006 Sep2025-05-29T20:32:57.927Z2019-03-27T01:46:01ZS-EPMC15947281695429510.1128/JCM.00866-0610.1128/jcm.00866-06