{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["100(13)"],"submitter":["Deslandes L"],"pubmed_abstract":["RRS1-R confers broad-spectrum resistance to several strains of the causal agent of bacterial wilt, Ralstonia solanacearum. Although genetically defined as recessive, this R gene encodes a protein whose structure combines the TIR-NBS-LRR domains found in several R proteins and a WRKY motif characteristic of some plant transcriptional factors and behaves as a dominant gene in transgenic susceptible plants. Here we show that PopP2, a R. solanacearum type III effector, which belongs to the YopJ/AvrRxv protein family, is the avirulence protein recognized by RRS1-R. Furthermore, an interaction between PopP2 and both RRS1-R and RRS1-S, present in the resistant Nd-1 and susceptible Col-5 Arabidopsis thaliana ecotypes, respectively, was detected by using the yeast split-ubiquitin two-hybrid system."],"journal":["Proceedings of the National Academy of Sciences of the United States of America"],"pagination":["8024-9"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC164706"],"repository":["biostudies-literature"],"pubmed_title":["Physical interaction between RRS1-R, a protein conferring resistance to bacterial wilt, and PopP2, a type III effector targeted to the plant nucleus."],"pmcid":["PMC164706"],"pubmed_authors":["Boucher C","Peeters N","Feng DX","Khounlotham M","Olivier J","Marco Y","Somssich I","Genin S","Deslandes L"],"additional_accession":[]},"is_claimable":false,"name":"Physical interaction between RRS1-R, a protein conferring resistance to bacterial wilt, and PopP2, a type III effector targeted to the plant nucleus.","description":"RRS1-R confers broad-spectrum resistance to several strains of the causal agent of bacterial wilt, Ralstonia solanacearum. Although genetically defined as recessive, this R gene encodes a protein whose structure combines the TIR-NBS-LRR domains found in several R proteins and a WRKY motif characteristic of some plant transcriptional factors and behaves as a dominant gene in transgenic susceptible plants. Here we show that PopP2, a R. solanacearum type III effector, which belongs to the YopJ/AvrRxv protein family, is the avirulence protein recognized by RRS1-R. Furthermore, an interaction between PopP2 and both RRS1-R and RRS1-S, present in the resistant Nd-1 and susceptible Col-5 Arabidopsis thaliana ecotypes, respectively, was detected by using the yeast split-ubiquitin two-hybrid system.","dates":{"release":"2003-01-01T00:00:00Z","publication":"2003 Jun","modification":"2025-04-26T15:50:30.801Z","creation":"2019-06-06T12:45:42Z"},"accession":"S-EPMC164706","cross_references":{"pubmed":["12788974"],"doi":["10.1073/pnas.1230660100"]}}