{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["75(3)"],"submitter":["Rosenau A"],"pubmed_abstract":["The ability of 111 Streptococcus agalactiae strains to bind to human fibrinogen was quantified. We correlated the percentages of bacteria that bound to immobilized fibrinogen with fibrinogen-binding (fbs) gene characteristics of strains and with clinical origin, serotypes, and phylogenetic positions of strains. Percentages varied from 0.4 to 29.9%. Fifty-five strains (49.5%) had the fbsB gene sensu stricto described by Gutekunst et al. (Infect. Immun., 72:3495-3504, 2004), allowing adhesion to human fibrinogen, and all of the other strains had an fgag variant gene. Ninety strains (81.1%) had a fbsA gene and 55 of them also had the fbsB gene. The other 21 strains (18.9%) had a truncated form of fbsA without the fbsB gene sensu stricto. The numbers of 48-nucleotide repeat sequences (rs) in t"],"journal":["Infection and immunity"],"pagination":["1310-7"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC1828567"],"repository":["biostudies-literature"],"pubmed_title":["Evaluation of the ability of Streptococcus agalactiae strains isolated from genital and neonatal specimens to bind to human fibrinogen and correlation with characteristics of the fbsA and fbsB genes."],"pmcid":["PMC1828567"],"pubmed_authors":["Quentin R","Rosenau A","Gannier F","Martins K","Lanotte P","van der Mee-Marquet N","Mereghetti L","Amor S"],"additional_accession":[]},"is_claimable":false,"name":"Evaluation of the ability of Streptococcus agalactiae strains isolated from genital and neonatal specimens to bind to human fibrinogen and correlation with characteristics of the fbsA and fbsB genes.","description":"The ability of 111 Streptococcus agalactiae strains to bind to human fibrinogen was quantified. We correlated the percentages of bacteria that bound to immobilized fibrinogen with fibrinogen-binding (fbs) gene characteristics of strains and with clinical origin, serotypes, and phylogenetic positions of strains. Percentages varied from 0.4 to 29.9%. Fifty-five strains (49.5%) had the fbsB gene sensu stricto described by Gutekunst et al. (Infect. Immun., 72:3495-3504, 2004), allowing adhesion to human fibrinogen, and all of the other strains had an fgag variant gene. Ninety strains (81.1%) had a fbsA gene and 55 of them also had the fbsB gene. The other 21 strains (18.9%) had a truncated form of fbsA without the fbsB gene sensu stricto. The numbers of 48-nucleotide repeat sequences (rs) in t","dates":{"release":"2007-01-01T00:00:00Z","publication":"2007 Mar","modification":"2025-05-29T20:34:01.91Z","creation":"2019-06-06T13:37:08Z"},"accession":"S-EPMC1828567","cross_references":{"pubmed":["17158903"],"doi":["10.1128/iai.00996-06","10.1128/IAI.00996-06"]}}