{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["van het Hoog M"],"funding":["NIAID NIH HHS"],"pagination":["R52"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC1896002"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["8(4)"],"pubmed_abstract":["Background
The 10.9x genomic sequence of Candida albicans, the most important human fungal pathogen, was published in 2004. Assembly 19 consisted of 412 supercontigs, of which 266 were a haploid set, since this fungus is diploid and contains an extensive degree of heterozygosity but lacks a complete sexual cycle. However, sequences of specific chromosomes were not determined.Results
Supercontigs from Assembly 19 (183, representing 98.4% of the sequence) were assigned to individual chromosomes purified by pulse-field gel electrophoresis and hybridized to DNA microarrays. Nine Assembly 19 supercontigs were found to contain markers from two different chromosomes. Assembly 21 contains the sequence of each of the eight chromosomes and was determined using a synteny analysis with"],"journal":["Genome biology"],"pubmed_title":["Assembly of the Candida albicans genome into sixteen supercontigs aligned on the eight chromosomes."],"pmcid":["PMC1896002"],"funding_grant_id":["R01 AI 16567","N01 AI05406","R01 AI016567"],"pubmed_authors":["Hogues H","Magee PT","Dignard D","Rast TJ","Chibana H","van het Hoog M","Berriman M","Cuomo C","Martchenko M","Whiteway M","Grindle S","Magee BB","Scherer S","Nantel A"],"additional_accession":[]},"is_claimable":false,"name":"Assembly of the Candida albicans genome into sixteen supercontigs aligned on the eight chromosomes.","description":"Background
The 10.9x genomic sequence of Candida albicans, the most important human fungal pathogen, was published in 2004. Assembly 19 consisted of 412 supercontigs, of which 266 were a haploid set, since this fungus is diploid and contains an extensive degree of heterozygosity but lacks a complete sexual cycle. However, sequences of specific chromosomes were not determined.Results
Supercontigs from Assembly 19 (183, representing 98.4% of the sequence) were assigned to individual chromosomes purified by pulse-field gel electrophoresis and hybridized to DNA microarrays. Nine Assembly 19 supercontigs were found to contain markers from two different chromosomes. Assembly 21 contains the sequence of each of the eight chromosomes and was determined using a synteny analysis with","dates":{"release":"2007-01-01T00:00:00Z","publication":"2007","modification":"2025-05-29T19:19:51.059Z","creation":"2019-03-27T02:04:12Z"},"accession":"S-EPMC1896002","cross_references":{"pubmed":["17419877"],"doi":["10.1186/gb-2007-8-4-r52"]}}