{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["81(24)"],"submitter":["Hwang HJ"],"pubmed_abstract":["In this study, we investigated changes in protein expression of fish cells induced by infection of infectious pancreatic necrosis virus (IPNV) using two-dimensional electrophoresis and matrix-assisted laser desorption-time of flight proton motive force analysis and identified a novel type of salmon annexin 1 that is induced in fish cells by infection with IPNV. Northern blotting showed that this annexin is overexpressed in IPNV-infected cells compared to control cells, and further analysis revealed that it has a 1,509-bp full-length cDNA sequence with an open reading frame encoding 339 amino acids (GenBank accession no. AY944135). Amino acid sequence analysis revealed that this protein belongs to the annexin 1 subfamily. By applying RNA interference, the mRNA levels of salmon annexin 1 wer"],"journal":["Journal of virology"],"pagination":["13816-24"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC2168874"],"repository":["biostudies-literature"],"pubmed_title":["Identification and functional analysis of salmon annexin 1 induced by a virus infection in a fish cell line."],"pmcid":["PMC2168874"],"pubmed_authors":["Park JW","Kim HG","Kim JY","Chung DK","Hwang HJ","Lee JM","Moon CH"],"additional_accession":[]},"is_claimable":false,"name":"Identification and functional analysis of salmon annexin 1 induced by a virus infection in a fish cell line.","description":"In this study, we investigated changes in protein expression of fish cells induced by infection of infectious pancreatic necrosis virus (IPNV) using two-dimensional electrophoresis and matrix-assisted laser desorption-time of flight proton motive force analysis and identified a novel type of salmon annexin 1 that is induced in fish cells by infection with IPNV. Northern blotting showed that this annexin is overexpressed in IPNV-infected cells compared to control cells, and further analysis revealed that it has a 1,509-bp full-length cDNA sequence with an open reading frame encoding 339 amino acids (GenBank accession no. AY944135). Amino acid sequence analysis revealed that this protein belongs to the annexin 1 subfamily. By applying RNA interference, the mRNA levels of salmon annexin 1 wer","dates":{"release":"2007-01-01T00:00:00Z","publication":"2007 Dec","modification":"2025-04-21T15:27:53.512Z","creation":"2019-03-27T02:22:21Z"},"accession":"S-EPMC2168874","cross_references":{"pubmed":["17881442"],"doi":["10.1128/jvi.02822-06","10.1128/JVI.02822-06"]}}