{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Rohlfs M"],"funding":["PHS HHS"],"pagination":["523-5"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC2391202"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["3(5)"],"pubmed_abstract":["The vast repertoire of toxic fungal secondary metabolites has long been assumed to have an evolved protective role against fungivory. It still remains elusive, however, whether fungi contain these compounds as an anti-predator adaptation. We demonstrate that loss of secondary metabolites in the soil mould Aspergillus nidulans causes, under the attack of the fungivorous springtail Folsomia candida, a disadvantage to the fungus. Springtails exhibited a distinct preference for feeding on a mutant deleted for LaeA, a global regulator of Aspergillus secondary metabolites. Consumption of the mutant yielded a reproductive advantage to the arthropod but detrimental effects on fungal biomass compared with a wild-type fungus capable of producing the entire arsenal of secondary metabolites. Our resul"],"journal":["Biology letters"],"pubmed_title":["Secondary chemicals protect mould from fungivory."],"pmcid":["PMC2391202"],"funding_grant_id":["1 R01 A1065728-01"],"pubmed_authors":["Albert M","Kempken F","Rohlfs M","Keller NP"],"additional_accession":[]},"is_claimable":false,"name":"Secondary chemicals protect mould from fungivory.","description":"The vast repertoire of toxic fungal secondary metabolites has long been assumed to have an evolved protective role against fungivory. It still remains elusive, however, whether fungi contain these compounds as an anti-predator adaptation. We demonstrate that loss of secondary metabolites in the soil mould Aspergillus nidulans causes, under the attack of the fungivorous springtail Folsomia candida, a disadvantage to the fungus. Springtails exhibited a distinct preference for feeding on a mutant deleted for LaeA, a global regulator of Aspergillus secondary metabolites. Consumption of the mutant yielded a reproductive advantage to the arthropod but detrimental effects on fungal biomass compared with a wild-type fungus capable of producing the entire arsenal of secondary metabolites. Our resul","dates":{"release":"2007-01-01T00:00:00Z","publication":"2007 Oct","modification":"2025-04-19T06:38:45.717Z","creation":"2019-03-27T00:15:10Z"},"accession":"S-EPMC2391202","cross_references":{"pubmed":["17686752"],"doi":["10.1098/rsbl.2007.0338"]}}