{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["64(Pt 6)"],"submitter":["Kaushal PS"],"pubmed_abstract":["The crystal structure of high-salt horse methaemoglobin has been determined at environmental relative humidities (r.h.) of 88, 79, 75 and 66%. The molecule is in the R state in the native and the r.h. 88% crystals. At r.h. 79%, the water content of the crystal is reduced and the molecule appears to move towards the R2 state. The crystals undergo a water-mediated transformation involving a doubling of one of the unit-cell parameters and an increase in water content when the environmental humidity is further reduced to r.h. 75%. The water content is now similar to that in the native crystals and the molecules are in the R state. The crystal structure at r.h. 66% is similar, but not identical, to that at r.h. 75%, but the solvent content is substantially reduced and the molecules have a quate"],"journal":["Acta crystallographica. Section F, Structural biology and crystallization communications"],"pagination":["463-9"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC2496843"],"repository":["biostudies-literature"],"pubmed_title":["Water-mediated variability in the structure of relaxed-state haemoglobin."],"pmcid":["PMC2496843"],"pubmed_authors":["Vijayan M","Sankaranarayanan R","Kaushal PS"],"additional_accession":[]},"is_claimable":false,"name":"Water-mediated variability in the structure of relaxed-state haemoglobin.","description":"The crystal structure of high-salt horse methaemoglobin has been determined at environmental relative humidities (r.h.) of 88, 79, 75 and 66%. The molecule is in the R state in the native and the r.h. 88% crystals. At r.h. 79%, the water content of the crystal is reduced and the molecule appears to move towards the R2 state. The crystals undergo a water-mediated transformation involving a doubling of one of the unit-cell parameters and an increase in water content when the environmental humidity is further reduced to r.h. 75%. The water content is now similar to that in the native crystals and the molecules are in the R state. The crystal structure at r.h. 66% is similar, but not identical, to that at r.h. 75%, but the solvent content is substantially reduced and the molecules have a quate","dates":{"release":"2008-01-01T00:00:00Z","publication":"2008 Jun","modification":"2025-06-01T11:59:32.488Z","creation":"2019-03-27T00:13:57Z"},"accession":"S-EPMC2496843","cross_references":{"pubmed":["18540052"],"doi":["10.1107/S1744309108013109","10.1107/s1744309108013109"]}}