{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Bhattacharya A"],"funding":["NINDS NIH HHS"],"pagination":["339"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC2533028"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["9"],"pubmed_abstract":["<h4>Background</h4>Innumerable biological investigations require comparing collections of molecules, cells or organisms to one another with respect to one or more of their properties. Almost all of these comparisons are performed manually, which can be susceptible to inadvertent bias as well as miss subtle effects. The development and application of computer-assisted analytical and interpretive tools could help address these issues and thereby dramatically improve these investigations.<h4>Results</h4>We have developed novel computer-assisted analytical and interpretive tools and applied them to recent studies examining the ability of 3-repeat and 4-repeat tau to regulate the dynamic behavior of microtubules in vitro. More specifically, we have developed an automated and objective method to"],"journal":["BMC bioinformatics"],"pubmed_title":["A general modeling and visualization tool for comparing different members of a group: application to studying tau-mediated regulation of microtubule dynamics."],"pmcid":["PMC2533028"],"funding_grant_id":["NS-13560","R01 NS013560","NS-35010","R01 NS035010"],"pubmed_authors":["Singh AK","LeBoeuf A","Bhattacharya A","Levy S","Feinstein SC","Gaylord M","Wilson L"],"additional_accession":[]},"is_claimable":false,"name":"A general modeling and visualization tool for comparing different members of a group: application to studying tau-mediated regulation of microtubule dynamics.","description":"<h4>Background</h4>Innumerable biological investigations require comparing collections of molecules, cells or organisms to one another with respect to one or more of their properties. Almost all of these comparisons are performed manually, which can be susceptible to inadvertent bias as well as miss subtle effects. The development and application of computer-assisted analytical and interpretive tools could help address these issues and thereby dramatically improve these investigations.<h4>Results</h4>We have developed novel computer-assisted analytical and interpretive tools and applied them to recent studies examining the ability of 3-repeat and 4-repeat tau to regulate the dynamic behavior of microtubules in vitro. More specifically, we have developed an automated and objective method to","dates":{"release":"2008-01-01T00:00:00Z","publication":"2008 Aug","modification":"2025-04-04T10:42:17.496Z","creation":"2019-03-27T00:16:32Z"},"accession":"S-EPMC2533028","cross_references":{"pubmed":["18700022"],"doi":["10.1186/1471-2105-9-339"]}}