{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Huang Q"],"funding":["NCI NIH HHS","NIGMS NIH HHS"],"pagination":["543-5"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC2537461"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["8(3)"],"pubmed_abstract":["[reaction: see text]. The total synthesis of (+/-)-bipinnatin J was achieved through a concise route that features the use of a silver ion promoted S(N)1-type gamma-alkylation of a siloxyfuran and a diastereoselective Cr(II)-mediated macrocyclization to provide bipinnatin J (1), wherein the remote furanone stereocenter at C10 induced the relative stereochemistry of the two additional stereocenters."],"journal":["Organic letters"],"pubmed_title":["Total synthesis of (+/-)-bipinnatin J."],"pmcid":["PMC2537461"],"funding_grant_id":["R01 GM69990","R01 CA101438","R01 CA101438-09","R01 CA101438-08","R01 CA101438-07","R01 CA101438-06","R01 CA101438-05"],"pubmed_authors":["Rawal VH","Huang Q"],"additional_accession":[]},"is_claimable":false,"name":"Total synthesis of (+/-)-bipinnatin J.","description":"[reaction: see text]. The total synthesis of (+/-)-bipinnatin J was achieved through a concise route that features the use of a silver ion promoted S(N)1-type gamma-alkylation of a siloxyfuran and a diastereoselective Cr(II)-mediated macrocyclization to provide bipinnatin J (1), wherein the remote furanone stereocenter at C10 induced the relative stereochemistry of the two additional stereocenters.","dates":{"release":"2006-01-01T00:00:00Z","publication":"2006 Feb","modification":"2025-04-04T13:10:10.185Z","creation":"2019-03-27T00:16:36Z"},"accession":"S-EPMC2537461","cross_references":{"pubmed":["16435880"],"doi":["10.1021/ol053054s"]}}