biostudies-literatureUnknown9Kaur M<h4>Background</h4>About 5% of western populations are afflicted by autoimmune diseases many of which are affected by sex hormones. Autoimmune diseases are complex and involve many genes. Identifying these disease-associated genes contributes to development of more effective therapies. Also, association studies frequently imply genomic regions that contain disease-associated genes but fall short of pinpointing these genes. The identification of disease-associated genes has always been challenging and to date there is no universal and effective method developed.<h4>Results</h4>We have developed a method to prioritize disease-associated genes for diseases affected strongly by sex hormones. Our method uses various types of information available for the genes, but no information that directly BMC genomics481https://www.ebi.ac.uk/biostudies/studies/S-EPMC2592250biostudies-literaturePrioritizing genes of potential relevance to diseases affected by sex hormones: an example of myasthenia gravis.PMC2592250Schmeier SMacPherson CRHide WABajic VBWillcox NKaur MTaylor SHofmann OfalsePrioritizing genes of potential relevance to diseases affected by sex hormones: an example of myasthenia gravis.<h4>Background</h4>About 5% of western populations are afflicted by autoimmune diseases many of which are affected by sex hormones. Autoimmune diseases are complex and involve many genes. Identifying these disease-associated genes contributes to development of more effective therapies. Also, association studies frequently imply genomic regions that contain disease-associated genes but fall short of pinpointing these genes. The identification of disease-associated genes has always been challenging and to date there is no universal and effective method developed.<h4>Results</h4>We have developed a method to prioritize disease-associated genes for diseases affected strongly by sex hormones. Our method uses various types of information available for the genes, but no information that directly 2008-01-01T00:00:00Z2008 Oct2025-05-29T19:43:14.808Z2025-05-29T19:43:14.808ZS-EPMC25922501885173410.1186/1471-2164-9-481