{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Rolain JM"],"funding":["Swiss National Science Foundation"],"pagination":["1"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC2629466"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["4"],"pubmed_abstract":["<h4>Background</h4>Staphylococcus aureus is a major human pathogen responsible for a variety of nosocomial and community-acquired infections. Recent reports show that the prevalence of Methicillin-Resistant S. aureus (MRSA) infections in cystic fibrosis (CF) patients is increasing. In 2006 in Marseille, France, we have detected an atypical MRSA strain with a specific antibiotic susceptibility profile and a unique growth phenotype. Because of the clinical importance of the spread of such strain among CF patients we decided to sequence the genome of one representative isolate (strain CF-Marseille) to compare this to the published genome sequences. We also conducted a retrospective epidemiological analysis on all S. aureus isolated from 2002 to 2007 in CF patients from our institution.<h4>Res"],"journal":["Biology direct"],"pubmed_title":["Genomic analysis of an emerging multiresistant Staphylococcus aureus strain rapidly spreading in cystic fibrosis patients revealed the presence of an antibiotic inducible bacteriophage."],"pmcid":["PMC2629466"],"funding_grant_id":["103002"],"pubmed_authors":["Bittar F","Stremler N","Rolain JM","Dubus JC","Boniface S","Sarles J","Raoult D","Bosdure E","Mattenberger Y","Francois P","Richet H","Fournous G","Schrenzel J","Reynaud-Gaubert M","Hernandez D"],"additional_accession":[]},"is_claimable":false,"name":"Genomic analysis of an emerging multiresistant Staphylococcus aureus strain rapidly spreading in cystic fibrosis patients revealed the presence of an antibiotic inducible bacteriophage.","description":"<h4>Background</h4>Staphylococcus aureus is a major human pathogen responsible for a variety of nosocomial and community-acquired infections. Recent reports show that the prevalence of Methicillin-Resistant S. aureus (MRSA) infections in cystic fibrosis (CF) patients is increasing. In 2006 in Marseille, France, we have detected an atypical MRSA strain with a specific antibiotic susceptibility profile and a unique growth phenotype. Because of the clinical importance of the spread of such strain among CF patients we decided to sequence the genome of one representative isolate (strain CF-Marseille) to compare this to the published genome sequences. We also conducted a retrospective epidemiological analysis on all S. aureus isolated from 2002 to 2007 in CF patients from our institution.<h4>Res","dates":{"release":"2009-01-01T00:00:00Z","publication":"2009 Jan","modification":"2026-05-03T18:35:13.611Z","creation":"2019-03-27T00:20:19Z"},"accession":"S-EPMC2629466","cross_references":{"pubmed":["19144117"],"doi":["10.1186/1745-6150-4-1"]}}