biostudies-literatureUnknown53(7)Mataseje LFA total of 142 cefoxitin-resistant Escherichia coli isolates from water sources were collected across Canada. Multidrug resistance was observed in 65/142 (45.8%) isolates. The bla(CMY-2) gene was identified in 110/142 (77.5%) isolates. Sequencing of the chromosomal ampC promoter region showed mutations from the wild type, previously shown to hyperproduce AmpC. CMY-2-producing plasmids predominantly belonged to replicon groups I1-Igamma, A/C, and K/B. The majority of the E. coli isolates belonged to the nonvirulent phylogenetic groups A and B1.Antimicrobial agents and chemotherapy3126-30https://www.ebi.ac.uk/biostudies/studies/S-EPMC2704656biostudies-literatureCharacterization of cefoxitin-resistant Escherichia coli isolates from recreational beaches and private drinking water in Canada between 2004 and 2006.PMC2704656Baudry PZhanel GGCiebin BIrwin RMcGeer ACrago BSalvadori MMataseje LFLevallois PNeumann NARO Water Study GroupMichel PMcEwen SMulvey MRLouie MJamieson FBuzzelli MfalseCharacterization of cefoxitin-resistant Escherichia coli isolates from recreational beaches and private drinking water in Canada between 2004 and 2006.A total of 142 cefoxitin-resistant Escherichia coli isolates from water sources were collected across Canada. Multidrug resistance was observed in 65/142 (45.8%) isolates. The bla(CMY-2) gene was identified in 110/142 (77.5%) isolates. Sequencing of the chromosomal ampC promoter region showed mutations from the wild type, previously shown to hyperproduce AmpC. CMY-2-producing plasmids predominantly belonged to replicon groups I1-Igamma, A/C, and K/B. The majority of the E. coli isolates belonged to the nonvirulent phylogenetic groups A and B1.2009-01-01T00:00:00Z2009 Jul2024-10-18T05:04:43.506Z2019-03-27T00:23:17ZS-EPMC27046561939864710.1128/aac.01353-0810.1128/AAC.01353-08