{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Gopal SM"],"funding":["NIGMS NIH HHS"],"pagination":["1266-81"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC2822037"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["78(5)"],"pubmed_abstract":["The new coarse graining model PRIMO/PRIMONA for proteins and nucleic acids is proposed. This model combines one to several heavy atoms into coarse-grained sites that are chosen to allow an analytical, high-resolution reconstruction of all-atom models based on molecular bonding geometry constraints. The accuracy of proposed reconstruction method in terms of structure and energetics is tested and compared with other popular reconstruction methods for a variety of protein and nucleic acid test sets."],"journal":["Proteins"],"pubmed_title":["PRIMO/PRIMONA: a coarse-grained model for proteins and nucleic acids that preserves near-atomistic accuracy."],"pmcid":["PMC2822037"],"funding_grant_id":["R01 GM084953","R01 GM092949","GM 084953","R01 GM084953-02"],"pubmed_authors":["Cheng YM","Gopal SM","Mukherjee S","Feig M"],"additional_accession":[]},"is_claimable":false,"name":"PRIMO/PRIMONA: a coarse-grained model for proteins and nucleic acids that preserves near-atomistic accuracy.","description":"The new coarse graining model PRIMO/PRIMONA for proteins and nucleic acids is proposed. This model combines one to several heavy atoms into coarse-grained sites that are chosen to allow an analytical, high-resolution reconstruction of all-atom models based on molecular bonding geometry constraints. The accuracy of proposed reconstruction method in terms of structure and energetics is tested and compared with other popular reconstruction methods for a variety of protein and nucleic acid test sets.","dates":{"release":"2010-01-01T00:00:00Z","publication":"2010 Apr","modification":"2020-11-19T15:59:01Z","creation":"2019-03-27T00:14:06Z"},"accession":"S-EPMC2822037","cross_references":{"pubmed":["19967787"],"doi":["10.1002/prot.22645"]}}