{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["82(3)"],"submitter":["Campuzano-Zuluaga G"],"pubmed_abstract":["Thick film, the standard diagnostic procedure for malaria, is not always ordered promptly. A failsafe diagnostic strategy using an XE-2100 analyzer is proposed, and for this strategy, malaria diagnostic models for the XE-2100 were developed and tested for accuracy. Two hundred eighty-one samples were distributed into Plasmodium vivax, P. falciparum, and acute febrile syndrome groups for model construction. Model validation was performed using 60% of malaria cases and a composite control group of samples from AFS and healthy participants from endemic and non-endemic regions. For P. vivax, two observer-dependent models (accuracy = 95.3-96.9%), one non-observer-dependent model using built-in variables (accuracy = 94.7%), and one non-observer-dependent model using new and built-in variables (accuracy = 96.8%) were developed. For P. falciparum, two non-observer-dependent models (accuracies = 85% and 89%) were developed. These models could be used by health personnel or be integrated as a malaria alarm for the XE-2100 to prompt early malaria microscopic diagnosis."],"journal":["The American journal of tropical medicine and hygiene"],"pagination":["402-11"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC2829900"],"repository":["biostudies-literature"],"pubmed_title":["Design of malaria diagnostic criteria for the Sysmex XE-2100 hematology analyzer."],"pmcid":["PMC2829900"],"pubmed_authors":["Alvarez-Sanchez G","Valencia-Zuluaga LM","Escobar-Gallo GE","Pabon-Vidal A","Rios-Orrego AM","Campuzano-Zuluaga G","Blair-Trujillo S","Campuzano-Maya G","Miranda-Arboleda AF"],"additional_accession":[]},"is_claimable":false,"name":"Design of malaria diagnostic criteria for the Sysmex XE-2100 hematology analyzer.","description":"Thick film, the standard diagnostic procedure for malaria, is not always ordered promptly. A failsafe diagnostic strategy using an XE-2100 analyzer is proposed, and for this strategy, malaria diagnostic models for the XE-2100 were developed and tested for accuracy. Two hundred eighty-one samples were distributed into Plasmodium vivax, P. falciparum, and acute febrile syndrome groups for model construction. Model validation was performed using 60% of malaria cases and a composite control group of samples from AFS and healthy participants from endemic and non-endemic regions. For P. vivax, two observer-dependent models (accuracy = 95.3-96.9%), one non-observer-dependent model using built-in variables (accuracy = 94.7%), and one non-observer-dependent model using new and built-in variables (accuracy = 96.8%) were developed. For P. falciparum, two non-observer-dependent models (accuracies = 85% and 89%) were developed. These models could be used by health personnel or be integrated as a malaria alarm for the XE-2100 to prompt early malaria microscopic diagnosis.","dates":{"release":"2010-01-01T00:00:00Z","publication":"2010 Mar","modification":"2025-04-18T23:13:44.873Z","creation":"2019-03-27T00:28:56Z"},"accession":"S-EPMC2829900","cross_references":{"pubmed":["20207864"],"doi":["10.4269/ajtmh.2010.09-0464"]}}